Rotating antibiotics selects optimally against antibiotic resistance, in theory
The purpose of this paper is to use mathematical models to investigate the claim made in the medical literature over a decade ago that the routine rotation of antibiotics in an intensive care unit (ICU) will select against the evolution and spread of antibiotic-resistant pathogens. In contrast, pr...
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Main Authors: | Robert E. Beardmore, Rafael Peña-Miller |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2010-05-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2010.7.527 |
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