Preventive Vaccinations of Respiratory Infections during Lung Transplantation
Relevance. Lung transplantation is recognized as a method of treating terminal stages of lung disease when the drug therapy resource has been exhausted. In addition to the lack of material for transplantation, a serious problem of lung transplantation is the low graft survival rate. The main reasons...
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| Format: | Article |
| Language: | Russian |
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Numikom LLC
2020-09-01
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| Series: | Эпидемиология и вакцинопрофилактика |
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| Online Access: | https://www.epidemvac.ru/jour/article/view/1061 |
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| author | V. B. Polishchuk K. V. Mashilov A. A. Ryzhov |
| author_facet | V. B. Polishchuk K. V. Mashilov A. A. Ryzhov |
| author_sort | V. B. Polishchuk |
| collection | DOAJ |
| description | Relevance. Lung transplantation is recognized as a method of treating terminal stages of lung disease when the drug therapy resource has been exhausted. In addition to the lack of material for transplantation, a serious problem of lung transplantation is the low graft survival rate. The main reasons are infections and primary allograft failure. Aims. To consider the current state of the use of vaccine prophylaxis in the integrated management of patients before and after lung transplantation. Conclusions The prevention of respiratory infections in adult candidates for organ transplantation and recipients is recommended and included in many clinical protocols and recommendations, however, they are based mainly on studies performed on healthy individuals, and are poorly supported by the results obtained in the study of individuals who underwent complete internal organ transplantation. Also, the effectiveness of vaccination remains unexplored, taking into account the individual characteristics of the immune system and the state of population immunity in relation to vaccine-preventable infections. |
| format | Article |
| id | doaj-art-c9d3fd5074d64c0b97085ed62f665cb3 |
| institution | Kabale University |
| issn | 2073-3046 2619-0494 |
| language | Russian |
| publishDate | 2020-09-01 |
| publisher | Numikom LLC |
| record_format | Article |
| series | Эпидемиология и вакцинопрофилактика |
| spelling | doaj-art-c9d3fd5074d64c0b97085ed62f665cb32025-08-20T03:34:43ZrusNumikom LLCЭпидемиология и вакцинопрофилактика2073-30462619-04942020-09-0119410210810.31631/2073-3046-2020-19-4-102-108672Preventive Vaccinations of Respiratory Infections during Lung TransplantationV. B. Polishchuk0K. V. Mashilov1A. A. Ryzhov2I. I. Mechnikov Research Institute of Vaccines and SeraI. I. Mechnikov Research Institute of Vaccines and SeraI. I. Mechnikov Research Institute of Vaccines and SeraRelevance. Lung transplantation is recognized as a method of treating terminal stages of lung disease when the drug therapy resource has been exhausted. In addition to the lack of material for transplantation, a serious problem of lung transplantation is the low graft survival rate. The main reasons are infections and primary allograft failure. Aims. To consider the current state of the use of vaccine prophylaxis in the integrated management of patients before and after lung transplantation. Conclusions The prevention of respiratory infections in adult candidates for organ transplantation and recipients is recommended and included in many clinical protocols and recommendations, however, they are based mainly on studies performed on healthy individuals, and are poorly supported by the results obtained in the study of individuals who underwent complete internal organ transplantation. Also, the effectiveness of vaccination remains unexplored, taking into account the individual characteristics of the immune system and the state of population immunity in relation to vaccine-preventable infections.https://www.epidemvac.ru/jour/article/view/1061preventive vaccinationlung transplantationtransplantation complicationsrespiratory infections |
| spellingShingle | V. B. Polishchuk K. V. Mashilov A. A. Ryzhov Preventive Vaccinations of Respiratory Infections during Lung Transplantation Эпидемиология и вакцинопрофилактика preventive vaccination lung transplantation transplantation complications respiratory infections |
| title | Preventive Vaccinations of Respiratory Infections during Lung Transplantation |
| title_full | Preventive Vaccinations of Respiratory Infections during Lung Transplantation |
| title_fullStr | Preventive Vaccinations of Respiratory Infections during Lung Transplantation |
| title_full_unstemmed | Preventive Vaccinations of Respiratory Infections during Lung Transplantation |
| title_short | Preventive Vaccinations of Respiratory Infections during Lung Transplantation |
| title_sort | preventive vaccinations of respiratory infections during lung transplantation |
| topic | preventive vaccination lung transplantation transplantation complications respiratory infections |
| url | https://www.epidemvac.ru/jour/article/view/1061 |
| work_keys_str_mv | AT vbpolishchuk preventivevaccinationsofrespiratoryinfectionsduringlungtransplantation AT kvmashilov preventivevaccinationsofrespiratoryinfectionsduringlungtransplantation AT aaryzhov preventivevaccinationsofrespiratoryinfectionsduringlungtransplantation |