THE CONCERNS OF ROSUVASTATIN CLINICAL EFFICACY AND SAFETY

In the article the authors consider some concerns of clinical efficacy and safety of rosuvastatin - the most powerful representative of the group of statins. The review contains the results of clinical trials, demonstrating its high lipid-lowering efficacy, impact on surrogate and primary endpoints...

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Main Authors: V. V. Kukharchuk, P. P. Malyshev
Format: Article
Language:Russian
Published: InterMedservice 2013-06-01
Series:Евразийский Кардиологический Журнал
Subjects:
Online Access:https://www.heartj.asia/jour/article/view/5550
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author V. V. Kukharchuk
P. P. Malyshev
author_facet V. V. Kukharchuk
P. P. Malyshev
author_sort V. V. Kukharchuk
collection DOAJ
description In the article the authors consider some concerns of clinical efficacy and safety of rosuvastatin - the most powerful representative of the group of statins. The review contains the results of clinical trials, demonstrating its high lipid-lowering efficacy, impact on surrogate and primary endpoints in studies on primary and secondary prevention. They also discuss safety treatment concerns with this drug, and its possible side effects. The authors present data on the comparative efficacy and tolerability of generic form of rosuvastatin (Mertenil, Gedeon Richter) which had been received by Russian and foreign researchers, the evidence about the comparability of therapeutic efficacy and safety of the generic to the original form.
format Article
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spelling doaj-art-c9d36b8e249647f2b99cc6028157cddb2025-08-20T03:20:34ZrusInterMedserviceЕвразийский Кардиологический Журнал2225-16852305-07482013-06-0102354210.38109/2225-1685-2013-2-35-425547THE CONCERNS OF ROSUVASTATIN CLINICAL EFFICACY AND SAFETYV. V. Kukharchuk0P. P. Malyshev1Russian Cardiology Research ComplexRussian Cardiology Research ComplexIn the article the authors consider some concerns of clinical efficacy and safety of rosuvastatin - the most powerful representative of the group of statins. The review contains the results of clinical trials, demonstrating its high lipid-lowering efficacy, impact on surrogate and primary endpoints in studies on primary and secondary prevention. They also discuss safety treatment concerns with this drug, and its possible side effects. The authors present data on the comparative efficacy and tolerability of generic form of rosuvastatin (Mertenil, Gedeon Richter) which had been received by Russian and foreign researchers, the evidence about the comparability of therapeutic efficacy and safety of the generic to the original form.https://www.heartj.asia/jour/article/view/5550атеросклерозмертенилрозувастатинстатиныatherosclerosisrosuvastatinmertenilstatins
spellingShingle V. V. Kukharchuk
P. P. Malyshev
THE CONCERNS OF ROSUVASTATIN CLINICAL EFFICACY AND SAFETY
Евразийский Кардиологический Журнал
атеросклероз
мертенил
розувастатин
статины
atherosclerosis
rosuvastatin
mertenil
statins
title THE CONCERNS OF ROSUVASTATIN CLINICAL EFFICACY AND SAFETY
title_full THE CONCERNS OF ROSUVASTATIN CLINICAL EFFICACY AND SAFETY
title_fullStr THE CONCERNS OF ROSUVASTATIN CLINICAL EFFICACY AND SAFETY
title_full_unstemmed THE CONCERNS OF ROSUVASTATIN CLINICAL EFFICACY AND SAFETY
title_short THE CONCERNS OF ROSUVASTATIN CLINICAL EFFICACY AND SAFETY
title_sort concerns of rosuvastatin clinical efficacy and safety
topic атеросклероз
мертенил
розувастатин
статины
atherosclerosis
rosuvastatin
mertenil
statins
url https://www.heartj.asia/jour/article/view/5550
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