Proteomics Analysis of Peripheral Blood Mononuclear Cells from Patients in Early Dengue Infection Reveals Potential Markers of Subsequent Fluid Leakage

Proteomics Analysis of Peripheral Blood Mononuclear Cells from Patients in Early Dengue Infection Reveals Potential Markers of Subsequent Fluid Leakage

Infections caused by dengue virus (DENV) result in significant morbidity and mortality. A proportion of infected individuals develop dengue haemorrhagic fever (DHF) characterized by circulatory collapse and multiorgan failure. Early detection of individuals likely to develop DHF could lead to improv...

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Bibliographic Details
Main Authors: Nilanka Perera, Abhinav Kumar, Bevin Gangadharan, Diyanath Ranasinghe, Ananda Wijewickrama, Gathsaurie Neelika Malavige, Joanna L. Miller, Nicole Zitzmann
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Viruses
Subjects:
dengue
proteomics
dengue haemorrhagic fever
fluid leakage
disease severity
markers
Online Access:https://www.mdpi.com/1999-4915/17/6/805
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