A multicenter cross-sectional study to elucidate altered resting-state functional connectivity of the insular cortex in anorexia nervosa, segmented by functional localization

A multicenter cross-sectional study to elucidate altered resting-state functional connectivity of the insular cortex in anorexia nervosa, segmented by functional localization

Abstract Although changes in insular function have been thought to play a central role in the pathophysiology of anorexia nervosa (AN), due to factors such as insufficient sample size, there have been no studies examining changes in resting-state functional connectivity (rsFC) between insula and who...

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Main Authors: Yusuke Sudo, Rio Kamashita, Tsunehiko Takamura, Sayo Hamatani, Noriko Numata, Koji Matsumoto, Yasuhiro Sato, Yumi Hamamoto, Tomotaka Shoji, Tomohiko Muratsubaki, Motoaki Sugiura, Shin Fukudo, Michiko Kawabata, Momo Sunada, Tomomi Noda, Keima Tose, Masanori Isobe, Naoki Kodama, Shingo Kakeda, Masatoshi Takahashi, Hiroaki Adachi, Shu Takakura, Motoharu Gondo, Kazufumi Yoshihara, Yoshiya Moriguchi, Eiji Shimizu, Atsushi Sekiguchi, Yoshiyuki Hirano
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Eating disorder
Anorexia nervosa
Resting-state functional connectivity
Insula
Taste
Online Access:https://doi.org/10.1038/s41598-025-03641-0
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