Clinical Applications of Remote Ischemic Preconditioning
Ischemia-reperfusion injury is a composite of damage accumulated during reduced perfusion of an organ or tissue and the additional insult sustained during reperfusion. Such injury occurs in a wide variety of clinically important syndromes, such as ischemic heart disease and stroke, which are respons...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
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| Series: | Cardiology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2012/620681 |
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| _version_ | 1849683241531867136 |
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| author | Kristin Veighey Raymond J. MacAllister |
| author_facet | Kristin Veighey Raymond J. MacAllister |
| author_sort | Kristin Veighey |
| collection | DOAJ |
| description | Ischemia-reperfusion injury is a composite of damage accumulated during reduced perfusion of an organ or tissue and the additional insult sustained during reperfusion. Such injury occurs in a wide variety of clinically important syndromes, such as ischemic heart disease and stroke, which are responsible for a high degree of morbidity and mortality worldwide. Basic research has identified a number of interventions that stimulate innate resistance of tissues to ischemia-reperfusion injury. Here, we summarise the experimental and clinical trial data underpinning one of these “conditioning” strategies, the phenomenon of remote ischemic preconditioning. |
| format | Article |
| id | doaj-art-c9cd11c4d8614445ba8da3719674215d |
| institution | DOAJ |
| issn | 2090-8016 2090-0597 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cardiology Research and Practice |
| spelling | doaj-art-c9cd11c4d8614445ba8da3719674215d2025-08-20T03:23:57ZengWileyCardiology Research and Practice2090-80162090-05972012-01-01201210.1155/2012/620681620681Clinical Applications of Remote Ischemic PreconditioningKristin Veighey0Raymond J. MacAllister1University College London Centre for Nephrology, Royal Free Campus, Rowland Hill Street, London NW3 2PF, UKUniversity College London Centre for Clinical Pharmacology, Rayne Institute, 5 University Street, London WC1E 6JF, UKIschemia-reperfusion injury is a composite of damage accumulated during reduced perfusion of an organ or tissue and the additional insult sustained during reperfusion. Such injury occurs in a wide variety of clinically important syndromes, such as ischemic heart disease and stroke, which are responsible for a high degree of morbidity and mortality worldwide. Basic research has identified a number of interventions that stimulate innate resistance of tissues to ischemia-reperfusion injury. Here, we summarise the experimental and clinical trial data underpinning one of these “conditioning” strategies, the phenomenon of remote ischemic preconditioning.http://dx.doi.org/10.1155/2012/620681 |
| spellingShingle | Kristin Veighey Raymond J. MacAllister Clinical Applications of Remote Ischemic Preconditioning Cardiology Research and Practice |
| title | Clinical Applications of Remote Ischemic Preconditioning |
| title_full | Clinical Applications of Remote Ischemic Preconditioning |
| title_fullStr | Clinical Applications of Remote Ischemic Preconditioning |
| title_full_unstemmed | Clinical Applications of Remote Ischemic Preconditioning |
| title_short | Clinical Applications of Remote Ischemic Preconditioning |
| title_sort | clinical applications of remote ischemic preconditioning |
| url | http://dx.doi.org/10.1155/2012/620681 |
| work_keys_str_mv | AT kristinveighey clinicalapplicationsofremoteischemicpreconditioning AT raymondjmacallister clinicalapplicationsofremoteischemicpreconditioning |