New 3- hydrazonoindolin-2-one Cd(II) complexes with amino pyridine ligands, Synthesis, Characterization and biological activity evaluation
This research includes synthesis and characterization of some of Cd(II) complexes with (3-hydrazonoindolin-2-one)(HZI) ligand and amino pyridine ligands. Treatment equialmolar of CdCl2.2.5H2O and (HZI) ligand with two moles of n-aminopyridine (n-amp) (n:2,3,4) ligands afford a tetrahedral com...
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| Language: | English |
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Tikrit University
2020-03-01
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| Series: | Tikrit Journal of Pure Science |
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| Online Access: | https://tjpsj.org/index.php/tjps/article/view/234 |
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| author | Lubna W. Mohammed Ahmed A. Irzoqi |
| author_facet | Lubna W. Mohammed Ahmed A. Irzoqi |
| author_sort | Lubna W. Mohammed |
| collection | DOAJ |
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This research includes synthesis and characterization of some of Cd(II) complexes with (3-hydrazonoindolin-2-one)(HZI) ligand and amino pyridine ligands.
Treatment equialmolar of CdCl2.2.5H2O and (HZI) ligand with two moles of n-aminopyridine (n-amp) (n:2,3,4) ligands afford a tetrahedral complexes of the type [Cd(HZI)(n-amp)2]Cl2, where (HZI) ligand behaves as a bidentate chelating fashion through the N atom of azomethine group and O atom of carbonyl group. Whereas the (n-amp)(n: 2,3,4) was bonded monodentate mode through the N atom of heterocyclic ring.
The prepared complexes have been characterized by molar conductivity, elemental analysis, infrared spectra and 1H-NMR and 13C-NMR spectra.
Also the evaluation of biological activity of the prepared complexes against two types of gram positive bacteria (Staphylococcus Epidermidis and Staphylococcus aureus) and (Citrobacer Freundii) and gram negative, all prepared complexes showed activity against Staphylococcus aureus more than amikacin, while the [Cd(HZI)(3-amp)2]Cl2 complex showed high activity against Staphylococcus Epidermidis and Citrobacter freundii more than another prepared complexes
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| format | Article |
| id | doaj-art-c9cc0aeb28db48e6b6f38d99630ad151 |
| institution | DOAJ |
| issn | 1813-1662 2415-1726 |
| language | English |
| publishDate | 2020-03-01 |
| publisher | Tikrit University |
| record_format | Article |
| series | Tikrit Journal of Pure Science |
| spelling | doaj-art-c9cc0aeb28db48e6b6f38d99630ad1512025-08-20T03:17:01ZengTikrit UniversityTikrit Journal of Pure Science1813-16622415-17262020-03-0125210.25130/tjps.v25i2.234New 3- hydrazonoindolin-2-one Cd(II) complexes with amino pyridine ligands, Synthesis, Characterization and biological activity evaluationLubna W. MohammedAhmed A. Irzoqi This research includes synthesis and characterization of some of Cd(II) complexes with (3-hydrazonoindolin-2-one)(HZI) ligand and amino pyridine ligands. Treatment equialmolar of CdCl2.2.5H2O and (HZI) ligand with two moles of n-aminopyridine (n-amp) (n:2,3,4) ligands afford a tetrahedral complexes of the type [Cd(HZI)(n-amp)2]Cl2, where (HZI) ligand behaves as a bidentate chelating fashion through the N atom of azomethine group and O atom of carbonyl group. Whereas the (n-amp)(n: 2,3,4) was bonded monodentate mode through the N atom of heterocyclic ring. The prepared complexes have been characterized by molar conductivity, elemental analysis, infrared spectra and 1H-NMR and 13C-NMR spectra. Also the evaluation of biological activity of the prepared complexes against two types of gram positive bacteria (Staphylococcus Epidermidis and Staphylococcus aureus) and (Citrobacer Freundii) and gram negative, all prepared complexes showed activity against Staphylococcus aureus more than amikacin, while the [Cd(HZI)(3-amp)2]Cl2 complex showed high activity against Staphylococcus Epidermidis and Citrobacter freundii more than another prepared complexes https://tjpsj.org/index.php/tjps/article/view/234Isatinshiff basecadmiumaminopyridinebiological activity |
| spellingShingle | Lubna W. Mohammed Ahmed A. Irzoqi New 3- hydrazonoindolin-2-one Cd(II) complexes with amino pyridine ligands, Synthesis, Characterization and biological activity evaluation Tikrit Journal of Pure Science Isatin shiff base cadmium aminopyridine biological activity |
| title | New 3- hydrazonoindolin-2-one Cd(II) complexes with amino pyridine ligands, Synthesis, Characterization and biological activity evaluation |
| title_full | New 3- hydrazonoindolin-2-one Cd(II) complexes with amino pyridine ligands, Synthesis, Characterization and biological activity evaluation |
| title_fullStr | New 3- hydrazonoindolin-2-one Cd(II) complexes with amino pyridine ligands, Synthesis, Characterization and biological activity evaluation |
| title_full_unstemmed | New 3- hydrazonoindolin-2-one Cd(II) complexes with amino pyridine ligands, Synthesis, Characterization and biological activity evaluation |
| title_short | New 3- hydrazonoindolin-2-one Cd(II) complexes with amino pyridine ligands, Synthesis, Characterization and biological activity evaluation |
| title_sort | new 3 hydrazonoindolin 2 one cd ii complexes with amino pyridine ligands synthesis characterization and biological activity evaluation |
| topic | Isatin shiff base cadmium aminopyridine biological activity |
| url | https://tjpsj.org/index.php/tjps/article/view/234 |
| work_keys_str_mv | AT lubnawmohammed new3hydrazonoindolin2onecdiicomplexeswithaminopyridineligandssynthesischaracterizationandbiologicalactivityevaluation AT ahmedairzoqi new3hydrazonoindolin2onecdiicomplexeswithaminopyridineligandssynthesischaracterizationandbiologicalactivityevaluation |