Fentanyl Versus Lidocaine Intravenously to Attenuate Hemodynamic Effects of En-dotracheal Intubation
Background and objectives:Hemodynamic changes to laryngoscopy and endotracheal intubation may increase mor- bidity in the perioperative period. Those changes may become significant in patients with uncontrolled hypertension or heart diseases. In this study, we compared the efficacy of intravenous f...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Kurdistan Higher Council Of Medical Specialties
2023-05-01
|
| Series: | Advanced Medical Journal |
| Subjects: | |
| Online Access: | https://amj.khcms.edu.krd/index.php/main/article/view/227 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850147912445591552 |
|---|---|
| author | Hozan Abdulwahid Ahmed Amir Murad Khudadad Boujan Othman Ismat Abdulmajeed |
| author_facet | Hozan Abdulwahid Ahmed Amir Murad Khudadad Boujan Othman Ismat Abdulmajeed |
| author_sort | Hozan Abdulwahid Ahmed |
| collection | DOAJ |
| description |
Background and objectives:Hemodynamic changes to laryngoscopy and endotracheal intubation may increase mor- bidity in the perioperative period. Those changes may become significant in patients with uncontrolled hypertension or heart diseases. In this study, we compared the efficacy of intravenous fentanyl and intravenous lidocaine in attenuating the hemodynamic responses during laryngoscopy and intubation.
Methods: A total of 100 adult patients, American Society of Anesthesiologists physical status I and II from both gender aged 18 to 65 years undergoing various elective surgeries under general anesthesia, were included in this prospective, randomized, single-blind study. The patients were randomly divided into two equal groups, Group F received 1mcg/kg fentanyl IV 3 minutes before intubation, group L received 1mg/kg lidocaine IV 3 minutes before intubation. Patients in both groups were anesthetized with the same technique. heart rate, systolic, diastolic and mean blood pressure were monitored and recorded before giving the study drug, 3 minutes after giving the study drug, 3 minutes after intubation then 6 minutes after intubation.
Results: We evaluated 100 patients including 49 males and 51 females, 62 American Society of Anesthesiologists physical status I and 38 American Society of Anesthesiologists physical status II, there were significant differences between the two groups 3 and 6 minutes after intubation, F group had less rise in heart rate, systolic, diastolic and mean blood pressure than L group 3 minutes after induction and endotracheal intubation.
Conclusions:we concluded that fentanyl 1mcg/ kg IV had more and faster effect in blunting stress response to laryngoscopy and endotracheal intubation as compared to lidocaine 1mg/kg IV.
|
| format | Article |
| id | doaj-art-c9caf1152dfa4018b693b1eb505b2ef6 |
| institution | OA Journals |
| issn | 2958-8979 2957-3580 |
| language | English |
| publishDate | 2023-05-01 |
| publisher | Kurdistan Higher Council Of Medical Specialties |
| record_format | Article |
| series | Advanced Medical Journal |
| spelling | doaj-art-c9caf1152dfa4018b693b1eb505b2ef62025-08-20T02:27:24ZengKurdistan Higher Council Of Medical SpecialtiesAdvanced Medical Journal2958-89792957-35802023-05-015110.56056/amj.2019.77228Fentanyl Versus Lidocaine Intravenously to Attenuate Hemodynamic Effects of En-dotracheal Intubation Hozan Abdulwahid Ahmed0Amir Murad Khudadad Boujan1Othman Ismat Abdulmajeed2M.B.Ch. B, Erbil Training Center of Anesthesia and Intensive Care Unit.Assist. Prof., Consultant Anesthesiologist, College of Medicine, University of SulaimaniConsultant Anesthesiologist, College of Medicine, Hawler Medical University Background and objectives:Hemodynamic changes to laryngoscopy and endotracheal intubation may increase mor- bidity in the perioperative period. Those changes may become significant in patients with uncontrolled hypertension or heart diseases. In this study, we compared the efficacy of intravenous fentanyl and intravenous lidocaine in attenuating the hemodynamic responses during laryngoscopy and intubation. Methods: A total of 100 adult patients, American Society of Anesthesiologists physical status I and II from both gender aged 18 to 65 years undergoing various elective surgeries under general anesthesia, were included in this prospective, randomized, single-blind study. The patients were randomly divided into two equal groups, Group F received 1mcg/kg fentanyl IV 3 minutes before intubation, group L received 1mg/kg lidocaine IV 3 minutes before intubation. Patients in both groups were anesthetized with the same technique. heart rate, systolic, diastolic and mean blood pressure were monitored and recorded before giving the study drug, 3 minutes after giving the study drug, 3 minutes after intubation then 6 minutes after intubation. Results: We evaluated 100 patients including 49 males and 51 females, 62 American Society of Anesthesiologists physical status I and 38 American Society of Anesthesiologists physical status II, there were significant differences between the two groups 3 and 6 minutes after intubation, F group had less rise in heart rate, systolic, diastolic and mean blood pressure than L group 3 minutes after induction and endotracheal intubation. Conclusions:we concluded that fentanyl 1mcg/ kg IV had more and faster effect in blunting stress response to laryngoscopy and endotracheal intubation as compared to lidocaine 1mg/kg IV. https://amj.khcms.edu.krd/index.php/main/article/view/227Endotracheal intubationHemodynamic responseLaryngoscopyLidocaine |
| spellingShingle | Hozan Abdulwahid Ahmed Amir Murad Khudadad Boujan Othman Ismat Abdulmajeed Fentanyl Versus Lidocaine Intravenously to Attenuate Hemodynamic Effects of En-dotracheal Intubation Advanced Medical Journal Endotracheal intubation Hemodynamic response Laryngoscopy Lidocaine |
| title | Fentanyl Versus Lidocaine Intravenously to Attenuate Hemodynamic Effects of En-dotracheal Intubation |
| title_full | Fentanyl Versus Lidocaine Intravenously to Attenuate Hemodynamic Effects of En-dotracheal Intubation |
| title_fullStr | Fentanyl Versus Lidocaine Intravenously to Attenuate Hemodynamic Effects of En-dotracheal Intubation |
| title_full_unstemmed | Fentanyl Versus Lidocaine Intravenously to Attenuate Hemodynamic Effects of En-dotracheal Intubation |
| title_short | Fentanyl Versus Lidocaine Intravenously to Attenuate Hemodynamic Effects of En-dotracheal Intubation |
| title_sort | fentanyl versus lidocaine intravenously to attenuate hemodynamic effects of en dotracheal intubation |
| topic | Endotracheal intubation Hemodynamic response Laryngoscopy Lidocaine |
| url | https://amj.khcms.edu.krd/index.php/main/article/view/227 |
| work_keys_str_mv | AT hozanabdulwahidahmed fentanylversuslidocaineintravenouslytoattenuatehemodynamiceffectsofendotrachealintubation AT amirmuradkhudadadboujan fentanylversuslidocaineintravenouslytoattenuatehemodynamiceffectsofendotrachealintubation AT othmanismatabdulmajeed fentanylversuslidocaineintravenouslytoattenuatehemodynamiceffectsofendotrachealintubation |