Tire rubber-derived contaminants 6PPD and 6PPD-quinone reduce attachment and outgrowth of trophoblast spheroids onto endometrial epithelial cells

Tire rubber-derived contaminants 6PPD and 6PPD-quinone reduce attachment and outgrowth of trophoblast spheroids onto endometrial epithelial cells

N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD), a synthetic additive widely used in the rubber industry, and its oxidized product 6PPD-quinone (6PPDQ), have garnered widespread attention as an emerging hazardous chemicals owing to their potential detrimental effects on aquatic ecosystem a...

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Bibliographic Details
Main Authors: Jong Geol Lee, Seon Min Lee, Moonjung Hyun, Jeong Doo Heo
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
6PPD
6PPDQ
Endometrial receptivity
Trophoblast invasion
Spheroid attachment
Spheroid outgrowth
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325000806
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