Systemic treatments in atopic dermatitis in children
Atopic dermatitis (AD) is a very common skin disease caused by inflammatory reactions, in which the main symptoms of severe itching and recurrent eczema diminish quality of life. As epidermal barrier function and the immune system play a critical role in atopic dermatitis, promoting IgE-media...
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| Format: | Article |
| Language: | English |
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Hacettepe University Institute of Child Health
2023-12-01
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| Series: | The Turkish Journal of Pediatrics |
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| Online Access: | https://turkjpediatr.org/article/view/100 |
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| _version_ | 1850181919595036672 |
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| author | Deniz İlgün Gürel Özge Soyer Ümit Murat Şahiner |
| author_facet | Deniz İlgün Gürel Özge Soyer Ümit Murat Şahiner |
| author_sort | Deniz İlgün Gürel |
| collection | DOAJ |
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Atopic dermatitis (AD) is a very common skin disease caused by inflammatory reactions, in which the main symptoms of severe itching and recurrent eczema diminish quality of life. As epidermal barrier function and the immune system play a critical role in atopic dermatitis, promoting IgE-mediated sensitization can be the main targets of AD treatment. The goal of AD treatment should be to eliminate the symptoms and obtain longterm eczema control with a multi-step approach adapted to the severity of the disease. Basic management for all patients comprises the use of moisturisers and avoiding triggers. While topical therapy is effective for most children diagnosed with AD, there may also be children who require systemic therapy. The aim of this paper was to present an extensive review of the systemic agents commonly used in childhood atopic dermatitis which mainly target cutaneous inflammation.
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| format | Article |
| id | doaj-art-c9b9b93e26fb497abf55d5c3d20ae5b8 |
| institution | OA Journals |
| issn | 0041-4301 2791-6421 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | Hacettepe University Institute of Child Health |
| record_format | Article |
| series | The Turkish Journal of Pediatrics |
| spelling | doaj-art-c9b9b93e26fb497abf55d5c3d20ae5b82025-08-20T02:17:47ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212023-12-0165610.24953/turkjped.2023.203Systemic treatments in atopic dermatitis in childrenDeniz İlgün Gürel0Özge Soyer1Ümit Murat Şahiner2Department of Pediatric Allergy, Hacettepe University Faculty of Medicine, Ankara, Türkiye.Department of Pediatric Allergy, Hacettepe University Faculty of Medicine, Ankara, Türkiye.Department of Pediatric Allergy, Hacettepe University Faculty of Medicine, Ankara, Türkiye. Atopic dermatitis (AD) is a very common skin disease caused by inflammatory reactions, in which the main symptoms of severe itching and recurrent eczema diminish quality of life. As epidermal barrier function and the immune system play a critical role in atopic dermatitis, promoting IgE-mediated sensitization can be the main targets of AD treatment. The goal of AD treatment should be to eliminate the symptoms and obtain longterm eczema control with a multi-step approach adapted to the severity of the disease. Basic management for all patients comprises the use of moisturisers and avoiding triggers. While topical therapy is effective for most children diagnosed with AD, there may also be children who require systemic therapy. The aim of this paper was to present an extensive review of the systemic agents commonly used in childhood atopic dermatitis which mainly target cutaneous inflammation. https://turkjpediatr.org/article/view/100atopic dermatitis (AD)childrensystemic treatment |
| spellingShingle | Deniz İlgün Gürel Özge Soyer Ümit Murat Şahiner Systemic treatments in atopic dermatitis in children The Turkish Journal of Pediatrics atopic dermatitis (AD) children systemic treatment |
| title | Systemic treatments in atopic dermatitis in children |
| title_full | Systemic treatments in atopic dermatitis in children |
| title_fullStr | Systemic treatments in atopic dermatitis in children |
| title_full_unstemmed | Systemic treatments in atopic dermatitis in children |
| title_short | Systemic treatments in atopic dermatitis in children |
| title_sort | systemic treatments in atopic dermatitis in children |
| topic | atopic dermatitis (AD) children systemic treatment |
| url | https://turkjpediatr.org/article/view/100 |
| work_keys_str_mv | AT denizilgungurel systemictreatmentsinatopicdermatitisinchildren AT ozgesoyer systemictreatmentsinatopicdermatitisinchildren AT umitmuratsahiner systemictreatmentsinatopicdermatitisinchildren |