Periodontitis-induced neuroinflammation triggers IFITM3-Aβ axis to cause alzheimer’s disease-like pathology and cognitive decline
Abstract Background Periodontitis is a risk factor linked to Alzheimer’s disease (AD), and characterized by amyloid-beta (Aβ) pathology. Mounting evidence suggests a contributory role of periodontitis in the onset and progression of AD. Type I interferons are upregulated in Porphyromonas gingivalis...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | Alzheimer’s Research & Therapy |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13195-025-01818-3 |
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