Bleb-related endophthalmitis

Objective: To report the risk factors, diagnosis, and treatment of bleb-related infections. Methods: This is a case report. Results: Two patients presented with acute pain, redness, and blurring of vision in the left eye. Both had undergone trabeculectomy with mitomycin C (MMC) for advanced ch...

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Main Authors: Angelito Braulio F. de Venecia III, MD, Ruben Lim Bon Siong,MD, Margarita Lat-Luna, MD
Format: Article
Language:English
Published: Philippine Academy of Ophthalmology 2008-12-01
Series:Philippine Journal of Ophthalmology
Subjects:
Online Access:https://paojournal.com/index.php/pjo/article/view/323
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author Angelito Braulio F. de Venecia III, MD
Ruben Lim Bon Siong,MD
Margarita Lat-Luna, MD
author_facet Angelito Braulio F. de Venecia III, MD
Ruben Lim Bon Siong,MD
Margarita Lat-Luna, MD
author_sort Angelito Braulio F. de Venecia III, MD
collection DOAJ
description Objective: To report the risk factors, diagnosis, and treatment of bleb-related infections. Methods: This is a case report. Results: Two patients presented with acute pain, redness, and blurring of vision in the left eye. Both had undergone trabeculectomy with mitomycin C (MMC) for advanced chronic angle-closure glaucoma several years ago and were lost to follow-up. On consultation, both had severe conjunctival congestion, with severe anterior-chamber (AC) reaction, and hypopyon. The cystic blebs were thinned out with visible infiltrates. Ocular ultrasound revealed vitreous cells. Culture and sensitivity tests confirmed the presence of blebitis with secondary endophthalmitis. Both patients were treated with intravenous moxifloxacin, atropine sulfate and moxifloxacin eye drops. Upon control of infection, they were started on topical steroid. Both responded well to treatment. Conclusion: Bleb-related infection is one of the complications of glaucoma filtration surgery that clinicians should consider when presented with complaints of acute pain, redness, and blurring of vision following trabeculectomy. Diagnosis should include staining, culture and sensitivity studies. Prompt treatment with broad-spectrum antibiotic is paramount to preserve vision.
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spelling doaj-art-c9984424428641c7987b7ace0d7ffaab2025-08-20T03:40:22ZengPhilippine Academy of OphthalmologyPhilippine Journal of Ophthalmology0031-76592008-12-013326669323Bleb-related endophthalmitisAngelito Braulio F. de Venecia III, MD0Ruben Lim Bon Siong,MD1Margarita Lat-Luna, MD2Department of Ophthalmology and Visual Sciences University of the Philippines–Philippine General Hospital Manila, PhilippinesDepartment of Ophthalmology and Visual Sciences University of the Philippines–Philippine General Hospital Manila, PhilippinesDepartment of Ophthalmology and Visual Sciences University of the Philippines–Philippine General Hospital Manila, PhilippinesObjective: To report the risk factors, diagnosis, and treatment of bleb-related infections. Methods: This is a case report. Results: Two patients presented with acute pain, redness, and blurring of vision in the left eye. Both had undergone trabeculectomy with mitomycin C (MMC) for advanced chronic angle-closure glaucoma several years ago and were lost to follow-up. On consultation, both had severe conjunctival congestion, with severe anterior-chamber (AC) reaction, and hypopyon. The cystic blebs were thinned out with visible infiltrates. Ocular ultrasound revealed vitreous cells. Culture and sensitivity tests confirmed the presence of blebitis with secondary endophthalmitis. Both patients were treated with intravenous moxifloxacin, atropine sulfate and moxifloxacin eye drops. Upon control of infection, they were started on topical steroid. Both responded well to treatment. Conclusion: Bleb-related infection is one of the complications of glaucoma filtration surgery that clinicians should consider when presented with complaints of acute pain, redness, and blurring of vision following trabeculectomy. Diagnosis should include staining, culture and sensitivity studies. Prompt treatment with broad-spectrum antibiotic is paramount to preserve vision.https://paojournal.com/index.php/pjo/article/view/323blebtrabeculectomyendophthalmitisglaucomamitomycin c
spellingShingle Angelito Braulio F. de Venecia III, MD
Ruben Lim Bon Siong,MD
Margarita Lat-Luna, MD
Bleb-related endophthalmitis
Philippine Journal of Ophthalmology
bleb
trabeculectomy
endophthalmitis
glaucoma
mitomycin c
title Bleb-related endophthalmitis
title_full Bleb-related endophthalmitis
title_fullStr Bleb-related endophthalmitis
title_full_unstemmed Bleb-related endophthalmitis
title_short Bleb-related endophthalmitis
title_sort bleb related endophthalmitis
topic bleb
trabeculectomy
endophthalmitis
glaucoma
mitomycin c
url https://paojournal.com/index.php/pjo/article/view/323
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AT rubenlimbonsiongmd blebrelatedendophthalmitis
AT margaritalatlunamd blebrelatedendophthalmitis