Clinical Evaluation of the Effect of Aficamten on QT/QTc Interval in Healthy Participants
ABSTRACT Aficamten is a next‐in‐class, small‐molecule, cardiac myosin inhibitor in development for treating hypertrophic cardiomyopathy (HCM). This 2‐part study evaluated aficamten's impact on QTc interval in healthy participants. Part A (n = 10) was an open‐label study to find the appropriate...
Saved in:
| Main Authors: | Neha Maharao, Donghong Xu, Tyrell J. Simkins, Owen Bowles, Genzhou Liu, Youcef Benattia, Adrienne Griffith, Stephen B. Heitner, Stuart Kupfer, Polina German |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-04-01
|
| Series: | Clinical and Translational Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/cts.70218 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Abnormalities in electrocardiographic ventricular repolarization in patients with dengue virus infection
by: Rosemary Aparecida Furlan-Daniel, et al.
Published: (2019-08-01) -
Population prevalence and correlates of prolonged and shortened QTc intervals in a nationwide survey of adults in China: a report from Chinese arrhythmia epidemiology cross-sectional study
by: Li-Guo Tan, et al.
Published: (2025-07-01) -
QTc prolongation and dysrhythmia risk in emergency department patients administered ondansetron
by: Evan Lawyer, et al.
Published: (2025-06-01) -
Mexiletine in the Treatment of LQT2, LQT3, and Acquired LQTS: A Meta-Analysis
by: Dhiya Ihsan, et al.
Published: (2025-05-01) -
Prognostic significance of the Tpe/Qtc ratio in predicting major adverse cardiac events in acute STEMI patients
by: Evren Dal, et al.
Published: (2025-07-01)