Management of Mild‐to‐Moderate Atopic Dermatitis With Topical Treatments by Dermatologists: A Questionnaire‐Based Study
ABSTRACT Background Atopic dermatitis (AD) is a chronic, immune‐mediated, inflammatory skin disorder affecting a heterogeneous population. Most patients with mild‐to‐moderate AD are treated with topical medication. Objectives To gain an understanding of the management of mild‐to‐moderate AD with top...
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Wiley
2025-06-01
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| Series: | JEADV Clinical Practice |
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| Online Access: | https://doi.org/10.1002/jvc2.611 |
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| author | Lawrence F. Eichenfield Linda F. Stein Gold Adelaide A. Hebert Lyn Guenther Yuliya Valdman‐Grinshpoun Dan Ben‐Amitai Roni P. Dodiuk‐Gad Michael J. Cork Valeria Aoki Chia‐Yu Chu Jianzhong Zhang Lin Ma Hidehisa Saeki Paula C. Luna Mark Jean‐Aan Koh |
| author_facet | Lawrence F. Eichenfield Linda F. Stein Gold Adelaide A. Hebert Lyn Guenther Yuliya Valdman‐Grinshpoun Dan Ben‐Amitai Roni P. Dodiuk‐Gad Michael J. Cork Valeria Aoki Chia‐Yu Chu Jianzhong Zhang Lin Ma Hidehisa Saeki Paula C. Luna Mark Jean‐Aan Koh |
| author_sort | Lawrence F. Eichenfield |
| collection | DOAJ |
| description | ABSTRACT Background Atopic dermatitis (AD) is a chronic, immune‐mediated, inflammatory skin disorder affecting a heterogeneous population. Most patients with mild‐to‐moderate AD are treated with topical medication. Objectives To gain an understanding of the management of mild‐to‐moderate AD with topical treatments by examining the practices of dermatologists worldwide using a questionnaire. Methods Participants from North America, the Middle East, Asia, South America and the United Kingdom completed an electronic questionnaire composed of 43 questions assessing their clinical practice with topical treatment for patients with mild‐to‐moderate AD among different age groups ( < 2, 2−12 and > 12 years) and disease severity (mild or moderate AD). Results Seventeen dermatologists completed the questionnaire. For patients of all ages with mild‐to‐moderate AD, nearly all participants indicated that topical corticosteroids (TCSs) are the first‐line topical treatment for a duration of ≤ 4 weeks before reassessment. Less‐potent TCSs were preferred for younger patients and for sensitive regions of the body. Time until treatment re‐evaluation was guided by disease severity: the greater the disease severity, the shorter the time until re‐evaluation (1 week to 4 months). In all age groups, after initial treatment, most participants would continue the regimen previously prescribed, switch to a non‐TCS agent (e.g., a topical calcineurin inhibitor, crisaborole or topical JAK inhibitor), or reduce the dose. All participants would utilize TCSs with or without non‐TCS agents for treating flares depending on patient age and affected region(s) of the skin. Infection, drug‐related adverse effects, worsening AD, corticophobia and limited access to topical pharmacologic treatment were the main reasons for deviation from the standard regimen. Conclusions Management of mild‐to‐moderate AD in practice is influenced by several patient‐specific factors, access to specialist care and therapies, safety concerns and limitations associated with treatment options. |
| format | Article |
| id | doaj-art-c97ad461f3df4fbfa629ac7d61887915 |
| institution | DOAJ |
| issn | 2768-6566 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Wiley |
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| series | JEADV Clinical Practice |
| spelling | doaj-art-c97ad461f3df4fbfa629ac7d618879152025-08-20T03:06:53ZengWileyJEADV Clinical Practice2768-65662025-06-014247148110.1002/jvc2.611Management of Mild‐to‐Moderate Atopic Dermatitis With Topical Treatments by Dermatologists: A Questionnaire‐Based StudyLawrence F. Eichenfield0Linda F. Stein Gold1Adelaide A. Hebert2Lyn Guenther3Yuliya Valdman‐Grinshpoun4Dan Ben‐Amitai5Roni P. Dodiuk‐Gad6Michael J. Cork7Valeria Aoki8Chia‐Yu Chu9Jianzhong Zhang10Lin Ma11Hidehisa Saeki12Paula C. Luna13Mark Jean‐Aan Koh14Departments of Dermatology and Pediatrics University of California San Diego and Rady Children's Hospital‐San Diego San Diego California USAHenry Ford Health System Detroit Michigan USAUTHealth McGovern Medical School Houston Texas USADepartment of Dermatology Western University London Ontario CanadaDepartment of Dermatology Soroka University Medical Center Beer Sheva IsraelSackler Faculty of Medicine Tel Aviv University Tel Aviv IsraelDepartment of Dermatology University of Toronto Toronto Ontario CanadaSheffield Dermatology Research and Department of Infection, Immunity and Cardiovascular Disease University of Sheffield Sheffield UKDepartment of Dermatology University of São Paulo School of Medicine São Paulo BrazilDepartment of Dermatology National Taiwan University Hospital and National Taiwan University College of Medicine Taipei TaiwanDepartment of Dermatology Peking University People's Hospital Beijing ChinaDepartment of Dermatology Beijing Children's Hospital, National Center for Children's Health Capital Medical University Beijing ChinaDepartment of Dermatology Nippon Medical School Tokyo JapanDepartment of Dermatology Hospital Alemán Buenos Aires ArgentinaDepartment of Dermatology KK Women's and Children's Hospital Singapore SingaporeABSTRACT Background Atopic dermatitis (AD) is a chronic, immune‐mediated, inflammatory skin disorder affecting a heterogeneous population. Most patients with mild‐to‐moderate AD are treated with topical medication. Objectives To gain an understanding of the management of mild‐to‐moderate AD with topical treatments by examining the practices of dermatologists worldwide using a questionnaire. Methods Participants from North America, the Middle East, Asia, South America and the United Kingdom completed an electronic questionnaire composed of 43 questions assessing their clinical practice with topical treatment for patients with mild‐to‐moderate AD among different age groups ( < 2, 2−12 and > 12 years) and disease severity (mild or moderate AD). Results Seventeen dermatologists completed the questionnaire. For patients of all ages with mild‐to‐moderate AD, nearly all participants indicated that topical corticosteroids (TCSs) are the first‐line topical treatment for a duration of ≤ 4 weeks before reassessment. Less‐potent TCSs were preferred for younger patients and for sensitive regions of the body. Time until treatment re‐evaluation was guided by disease severity: the greater the disease severity, the shorter the time until re‐evaluation (1 week to 4 months). In all age groups, after initial treatment, most participants would continue the regimen previously prescribed, switch to a non‐TCS agent (e.g., a topical calcineurin inhibitor, crisaborole or topical JAK inhibitor), or reduce the dose. All participants would utilize TCSs with or without non‐TCS agents for treating flares depending on patient age and affected region(s) of the skin. Infection, drug‐related adverse effects, worsening AD, corticophobia and limited access to topical pharmacologic treatment were the main reasons for deviation from the standard regimen. Conclusions Management of mild‐to‐moderate AD in practice is influenced by several patient‐specific factors, access to specialist care and therapies, safety concerns and limitations associated with treatment options.https://doi.org/10.1002/jvc2.611atopic dermatitisdermatologic therapyeczema |
| spellingShingle | Lawrence F. Eichenfield Linda F. Stein Gold Adelaide A. Hebert Lyn Guenther Yuliya Valdman‐Grinshpoun Dan Ben‐Amitai Roni P. Dodiuk‐Gad Michael J. Cork Valeria Aoki Chia‐Yu Chu Jianzhong Zhang Lin Ma Hidehisa Saeki Paula C. Luna Mark Jean‐Aan Koh Management of Mild‐to‐Moderate Atopic Dermatitis With Topical Treatments by Dermatologists: A Questionnaire‐Based Study JEADV Clinical Practice atopic dermatitis dermatologic therapy eczema |
| title | Management of Mild‐to‐Moderate Atopic Dermatitis With Topical Treatments by Dermatologists: A Questionnaire‐Based Study |
| title_full | Management of Mild‐to‐Moderate Atopic Dermatitis With Topical Treatments by Dermatologists: A Questionnaire‐Based Study |
| title_fullStr | Management of Mild‐to‐Moderate Atopic Dermatitis With Topical Treatments by Dermatologists: A Questionnaire‐Based Study |
| title_full_unstemmed | Management of Mild‐to‐Moderate Atopic Dermatitis With Topical Treatments by Dermatologists: A Questionnaire‐Based Study |
| title_short | Management of Mild‐to‐Moderate Atopic Dermatitis With Topical Treatments by Dermatologists: A Questionnaire‐Based Study |
| title_sort | management of mild to moderate atopic dermatitis with topical treatments by dermatologists a questionnaire based study |
| topic | atopic dermatitis dermatologic therapy eczema |
| url | https://doi.org/10.1002/jvc2.611 |
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