Visualizing Vertebrate Embryos with Episcopic 3D Imaging Techniques
The creation of highly detailed, three-dimensional (3D) computer models is essential in order to understand the evolution and development of vertebrate embryos, and the pathogenesis of hereditary diseases. A still-increasing number of methods allow for generating digital volume data sets as the basi...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/tsw.2009.154 |
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| _version_ | 1850173016971935744 |
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| author | Stefan H. Geyer Timothy J. Mohun Wolfgang J. Weninger |
| author_facet | Stefan H. Geyer Timothy J. Mohun Wolfgang J. Weninger |
| author_sort | Stefan H. Geyer |
| collection | DOAJ |
| description | The creation of highly detailed, three-dimensional (3D) computer models is essential in order to understand the evolution and development of vertebrate embryos, and the pathogenesis of hereditary diseases. A still-increasing number of methods allow for generating digital volume data sets as the basis of virtual 3D computer models. This work aims to provide a brief overview about modern volume data–generation techniques, focusing on episcopic 3D imaging methods. The technical principles, advantages, and problems of episcopic 3D imaging are described. The strengths and weaknesses in its ability to visualize embryo anatomy and labeled gene product patterns, specifically, are discussed. |
| format | Article |
| id | doaj-art-c974ded16f824841a7c4d956b4eec957 |
| institution | OA Journals |
| issn | 1537-744X |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-c974ded16f824841a7c4d956b4eec9572025-08-20T02:19:57ZengWileyThe Scientific World Journal1537-744X2009-01-0191423143710.1100/tsw.2009.154Visualizing Vertebrate Embryos with Episcopic 3D Imaging TechniquesStefan H. Geyer0Timothy J. Mohun1Wolfgang J. Weninger2Centre for Anatomy and Cell Biology, Medical University of Vienna, London, UKDevelopmental Biology Division, MRC National Institute for Medical Research, London, UKCentre for Anatomy and Cell Biology, Medical University of Vienna, London, UKThe creation of highly detailed, three-dimensional (3D) computer models is essential in order to understand the evolution and development of vertebrate embryos, and the pathogenesis of hereditary diseases. A still-increasing number of methods allow for generating digital volume data sets as the basis of virtual 3D computer models. This work aims to provide a brief overview about modern volume data–generation techniques, focusing on episcopic 3D imaging methods. The technical principles, advantages, and problems of episcopic 3D imaging are described. The strengths and weaknesses in its ability to visualize embryo anatomy and labeled gene product patterns, specifically, are discussed.http://dx.doi.org/10.1100/tsw.2009.154 |
| spellingShingle | Stefan H. Geyer Timothy J. Mohun Wolfgang J. Weninger Visualizing Vertebrate Embryos with Episcopic 3D Imaging Techniques The Scientific World Journal |
| title | Visualizing Vertebrate Embryos with Episcopic 3D Imaging Techniques |
| title_full | Visualizing Vertebrate Embryos with Episcopic 3D Imaging Techniques |
| title_fullStr | Visualizing Vertebrate Embryos with Episcopic 3D Imaging Techniques |
| title_full_unstemmed | Visualizing Vertebrate Embryos with Episcopic 3D Imaging Techniques |
| title_short | Visualizing Vertebrate Embryos with Episcopic 3D Imaging Techniques |
| title_sort | visualizing vertebrate embryos with episcopic 3d imaging techniques |
| url | http://dx.doi.org/10.1100/tsw.2009.154 |
| work_keys_str_mv | AT stefanhgeyer visualizingvertebrateembryoswithepiscopic3dimagingtechniques AT timothyjmohun visualizingvertebrateembryoswithepiscopic3dimagingtechniques AT wolfgangjweninger visualizingvertebrateembryoswithepiscopic3dimagingtechniques |