The Effect of Nutrient Deprivation on Markers of Oxidative Stress, Inflammation, and Transcriptome in Normal and Type-2 Diabetic Human Skeletal Muscle Myoblasts
Conclusions: Myoblast viability and density were lower in the nutrient-deprived conditions and in the FBS compared to the HS serum. The biomarker of oxidative stress was lower in the serum concentration in a scaled effect, yet higher in HS. The biomarker of inflammation was higher in the HSMM cell l...
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Journal of Nutrition and Metabolism |
| Online Access: | http://dx.doi.org/10.1155/jnme/6661176 |
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| author | Lael Ceriani Daniel E. Newmire Xavier F. Gonzales Jean Sparks Jose Guardiola Felix O. Omoruyi |
| author_facet | Lael Ceriani Daniel E. Newmire Xavier F. Gonzales Jean Sparks Jose Guardiola Felix O. Omoruyi |
| author_sort | Lael Ceriani |
| collection | DOAJ |
| description | Conclusions: Myoblast viability and density were lower in the nutrient-deprived conditions and in the FBS compared to the HS serum. The biomarker of oxidative stress was lower in the serum concentration in a scaled effect, yet higher in HS. The biomarker of inflammation was higher in the HSMM cell line, shorter incubation time period, and in FBS. HS used as a media may supply nutrients and hormonal confounders that may support or stress myoblast growth. |
| format | Article |
| id | doaj-art-c94171dcfe284f6aaf5da0322addcb6a |
| institution | OA Journals |
| issn | 2090-0732 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Nutrition and Metabolism |
| spelling | doaj-art-c94171dcfe284f6aaf5da0322addcb6a2025-08-20T02:20:40ZengWileyJournal of Nutrition and Metabolism2090-07322025-01-01202510.1155/jnme/6661176The Effect of Nutrient Deprivation on Markers of Oxidative Stress, Inflammation, and Transcriptome in Normal and Type-2 Diabetic Human Skeletal Muscle MyoblastsLael Ceriani0Daniel E. Newmire1Xavier F. Gonzales2Jean Sparks3Jose Guardiola4Felix O. Omoruyi5Department of Life SciencesSchool of Health Promotion and KinesiologyDepartment of Life SciencesDepartment of Health SciencesDepartment of Mathematics and StatisticsDepartment of Life SciencesConclusions: Myoblast viability and density were lower in the nutrient-deprived conditions and in the FBS compared to the HS serum. The biomarker of oxidative stress was lower in the serum concentration in a scaled effect, yet higher in HS. The biomarker of inflammation was higher in the HSMM cell line, shorter incubation time period, and in FBS. HS used as a media may supply nutrients and hormonal confounders that may support or stress myoblast growth.http://dx.doi.org/10.1155/jnme/6661176 |
| spellingShingle | Lael Ceriani Daniel E. Newmire Xavier F. Gonzales Jean Sparks Jose Guardiola Felix O. Omoruyi The Effect of Nutrient Deprivation on Markers of Oxidative Stress, Inflammation, and Transcriptome in Normal and Type-2 Diabetic Human Skeletal Muscle Myoblasts Journal of Nutrition and Metabolism |
| title | The Effect of Nutrient Deprivation on Markers of Oxidative Stress, Inflammation, and Transcriptome in Normal and Type-2 Diabetic Human Skeletal Muscle Myoblasts |
| title_full | The Effect of Nutrient Deprivation on Markers of Oxidative Stress, Inflammation, and Transcriptome in Normal and Type-2 Diabetic Human Skeletal Muscle Myoblasts |
| title_fullStr | The Effect of Nutrient Deprivation on Markers of Oxidative Stress, Inflammation, and Transcriptome in Normal and Type-2 Diabetic Human Skeletal Muscle Myoblasts |
| title_full_unstemmed | The Effect of Nutrient Deprivation on Markers of Oxidative Stress, Inflammation, and Transcriptome in Normal and Type-2 Diabetic Human Skeletal Muscle Myoblasts |
| title_short | The Effect of Nutrient Deprivation on Markers of Oxidative Stress, Inflammation, and Transcriptome in Normal and Type-2 Diabetic Human Skeletal Muscle Myoblasts |
| title_sort | effect of nutrient deprivation on markers of oxidative stress inflammation and transcriptome in normal and type 2 diabetic human skeletal muscle myoblasts |
| url | http://dx.doi.org/10.1155/jnme/6661176 |
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