Therapeutic potential of natural arginase modulators: mechanisms, challenges, and future directions

Therapeutic potential of natural arginase modulators: mechanisms, challenges, and future directions

Arginase (Arg) plays a pivotal role in numerous pathological processes, with its dysregulated expression being intricately associated with tumor progression and immune evasion. This review comprehensively examines the diversity, mechanisms, and clinical potential of natural Arg modulators, encompass...

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Bibliographic Details
Main Authors:	Ting Li, Jieying Wang, Huan Wang, Bowei Zhang, Lijuan Duan
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-04-01
Series:	Frontiers in Pharmacology
Subjects:	natural arginase modulator cancer therapy cardiovascular disease neuroprotection macrophage polarization
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1514400/full
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