Protective potential of mesenchymal stem cells against COVID-19 during pregnancy
SARS-CoV-2 causes COVID-19. COVID-19 has led to severe clinical illnesses and an unprecedented death toll. The virus induces immune inflammatory responses specifically cytokine storm in lungs. Several published reports indicated that pregnant females are less likely to develop severe symptoms compar...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-12-01
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| Series: | Future Science OA |
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| Online Access: | https://www.future-science.com/doi/10.2144/fsoa-2023-0179 |
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| author | Sihem Aouabdi Doaa Aboalola Samer Zakari Suliman Alwafi Taoufik Nedjadi Rawiah Alsiary |
| author_facet | Sihem Aouabdi Doaa Aboalola Samer Zakari Suliman Alwafi Taoufik Nedjadi Rawiah Alsiary |
| author_sort | Sihem Aouabdi |
| collection | DOAJ |
| description | SARS-CoV-2 causes COVID-19. COVID-19 has led to severe clinical illnesses and an unprecedented death toll. The virus induces immune inflammatory responses specifically cytokine storm in lungs. Several published reports indicated that pregnant females are less likely to develop severe symptoms compared with non-pregnant. Putative protective role of maternal blood circulating fetal mesenchymal stem cells (MSCs) has emerged and have been put forward as an explanation to alleviated symptoms. MSCs with immune-modulatory, anti-inflammatory and anti-viral roles, hold great potential for the treatment of COVID-19. MSCs could be an alternative to treat infections resulting from the SARS-CoV-2 and potential future outbreaks. This review focuses on the MSCs putative protective roles against COVID-19 in pregnant females. |
| format | Article |
| id | doaj-art-c93fafdeb95d41ac8c64b8f1cf9c945e |
| institution | OA Journals |
| issn | 2056-5623 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Future Science OA |
| spelling | doaj-art-c93fafdeb95d41ac8c64b8f1cf9c945e2025-08-20T02:26:09ZengTaylor & Francis GroupFuture Science OA2056-56232023-12-0110.2144/fsoa-2023-0179Protective potential of mesenchymal stem cells against COVID-19 during pregnancySihem Aouabdi0Doaa Aboalola1Samer Zakari2Suliman Alwafi3Taoufik Nedjadi4Rawiah Alsiary51King Abdullah International Medical Research Center, Jeddah, 21423, Saudi Arabia1King Abdullah International Medical Research Center, Jeddah, 21423, Saudi Arabia1King Abdullah International Medical Research Center, Jeddah, 21423, Saudi Arabia1King Abdullah International Medical Research Center, Jeddah, 21423, Saudi Arabia1King Abdullah International Medical Research Center, Jeddah, 21423, Saudi Arabia1King Abdullah International Medical Research Center, Jeddah, 21423, Saudi ArabiaSARS-CoV-2 causes COVID-19. COVID-19 has led to severe clinical illnesses and an unprecedented death toll. The virus induces immune inflammatory responses specifically cytokine storm in lungs. Several published reports indicated that pregnant females are less likely to develop severe symptoms compared with non-pregnant. Putative protective role of maternal blood circulating fetal mesenchymal stem cells (MSCs) has emerged and have been put forward as an explanation to alleviated symptoms. MSCs with immune-modulatory, anti-inflammatory and anti-viral roles, hold great potential for the treatment of COVID-19. MSCs could be an alternative to treat infections resulting from the SARS-CoV-2 and potential future outbreaks. This review focuses on the MSCs putative protective roles against COVID-19 in pregnant females.https://www.future-science.com/doi/10.2144/fsoa-2023-0179COVID-19MSCspregnancySARS-CoV-2transplantation |
| spellingShingle | Sihem Aouabdi Doaa Aboalola Samer Zakari Suliman Alwafi Taoufik Nedjadi Rawiah Alsiary Protective potential of mesenchymal stem cells against COVID-19 during pregnancy Future Science OA COVID-19 MSCs pregnancy SARS-CoV-2 transplantation |
| title | Protective potential of mesenchymal stem cells against COVID-19 during pregnancy |
| title_full | Protective potential of mesenchymal stem cells against COVID-19 during pregnancy |
| title_fullStr | Protective potential of mesenchymal stem cells against COVID-19 during pregnancy |
| title_full_unstemmed | Protective potential of mesenchymal stem cells against COVID-19 during pregnancy |
| title_short | Protective potential of mesenchymal stem cells against COVID-19 during pregnancy |
| title_sort | protective potential of mesenchymal stem cells against covid 19 during pregnancy |
| topic | COVID-19 MSCs pregnancy SARS-CoV-2 transplantation |
| url | https://www.future-science.com/doi/10.2144/fsoa-2023-0179 |
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