Aged Lewis rats exposed to low and moderate doses of rotenone are a good model for studying the process of protein aggregation and its effects upon central nervous system cell physiology
ABSTRACT Cell physiology is impaired before protein aggregation and this may be more relevant than inclusions themselves for neurodegeneration. The present study aimed to characterize an animal model to enable the analysis of the cell biology before and after protein aggregation. Ten-month-old Lewis...
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| Main Authors: | Michael F. Almeida, Carolliny M. Silva, Aline M. D’Unhao, Merari F. R. Ferrari |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Thieme Revinter Publicações
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| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016000900737&lng=en&tlng=en |
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