Seizure and Pulmonary Embolism: A Differential That Can Save a Life

Seizures is a relatively common presentation with a wide differential diagnosis. However, seizures presenting secondary to underlying pulmonary emboli are rare and, without prompt recognition and management, this easily treatable condition can be potentially fatal. The few available case reports dis...

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Main Authors: Seyedmohammad Pourshahid, Sneha Dedhia, Shakeeb Hakim, Mohamed Barakat, Dennis Genin
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Pulmonology
Online Access:http://dx.doi.org/10.1155/2017/3408795
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author Seyedmohammad Pourshahid
Sneha Dedhia
Shakeeb Hakim
Mohamed Barakat
Dennis Genin
author_facet Seyedmohammad Pourshahid
Sneha Dedhia
Shakeeb Hakim
Mohamed Barakat
Dennis Genin
author_sort Seyedmohammad Pourshahid
collection DOAJ
description Seizures is a relatively common presentation with a wide differential diagnosis. However, seizures presenting secondary to underlying pulmonary emboli are rare and, without prompt recognition and management, this easily treatable condition can be potentially fatal. The few available case reports discussing seizures and PE reveal a high mortality rate which underscores the importance of prompt diagnosis. A 38-year-old woman presented to the emergency room having experienced loss of consciousness and a generalized tonic-clonic seizure at home. In the emergency room, her presenting signs and symptoms included tachycardia, worsening dyspnea, mild hypoxemia, and elevated D-dimer. Pertinent history findings revealed she recently received depot hormonal contraceptive treatments. Her initial workup included an EKG which showed sinus tachycardia without evidence of right heart strain. Subsequently a chest CT with angiography revealed massive bilateral pulmonary emboli. DVT studies also revealed a unilateral acute DVT. The patient was promptly started on therapeutic anticoagulation and stabilized. Fortunately, the patient remained symptom-free and eventually was discharged with close follow-up. The goal of this report is to make clinicians more aware of the possibility that seizures, along with the appropriate clinical findings, can be caused by acute PE.
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spelling doaj-art-c93b457da63b43ca9da9cccaf52905e52025-08-20T02:19:34ZengWileyCase Reports in Pulmonology2090-68462090-68542017-01-01201710.1155/2017/34087953408795Seizure and Pulmonary Embolism: A Differential That Can Save a LifeSeyedmohammad Pourshahid0Sneha Dedhia1Shakeeb Hakim2Mohamed Barakat3Dennis Genin4Department of Medicine, Icahn School of Medicine at Mount Sinai/NYC Health + Hospitals/Queens, New York, NY, USADepartment of Medicine, Icahn School of Medicine at Mount Sinai/NYC Health + Hospitals/Queens, New York, NY, USADepartment of Medicine, Icahn School of Medicine at Mount Sinai/NYC Health + Hospitals/Queens, New York, NY, USADepartment of Medicine, Icahn School of Medicine at Mount Sinai/NYC Health + Hospitals/Queens, New York, NY, USADepartment of Medicine, Icahn School of Medicine at Mount Sinai/NYC Health + Hospitals/Queens, New York, NY, USASeizures is a relatively common presentation with a wide differential diagnosis. However, seizures presenting secondary to underlying pulmonary emboli are rare and, without prompt recognition and management, this easily treatable condition can be potentially fatal. The few available case reports discussing seizures and PE reveal a high mortality rate which underscores the importance of prompt diagnosis. A 38-year-old woman presented to the emergency room having experienced loss of consciousness and a generalized tonic-clonic seizure at home. In the emergency room, her presenting signs and symptoms included tachycardia, worsening dyspnea, mild hypoxemia, and elevated D-dimer. Pertinent history findings revealed she recently received depot hormonal contraceptive treatments. Her initial workup included an EKG which showed sinus tachycardia without evidence of right heart strain. Subsequently a chest CT with angiography revealed massive bilateral pulmonary emboli. DVT studies also revealed a unilateral acute DVT. The patient was promptly started on therapeutic anticoagulation and stabilized. Fortunately, the patient remained symptom-free and eventually was discharged with close follow-up. The goal of this report is to make clinicians more aware of the possibility that seizures, along with the appropriate clinical findings, can be caused by acute PE.http://dx.doi.org/10.1155/2017/3408795
spellingShingle Seyedmohammad Pourshahid
Sneha Dedhia
Shakeeb Hakim
Mohamed Barakat
Dennis Genin
Seizure and Pulmonary Embolism: A Differential That Can Save a Life
Case Reports in Pulmonology
title Seizure and Pulmonary Embolism: A Differential That Can Save a Life
title_full Seizure and Pulmonary Embolism: A Differential That Can Save a Life
title_fullStr Seizure and Pulmonary Embolism: A Differential That Can Save a Life
title_full_unstemmed Seizure and Pulmonary Embolism: A Differential That Can Save a Life
title_short Seizure and Pulmonary Embolism: A Differential That Can Save a Life
title_sort seizure and pulmonary embolism a differential that can save a life
url http://dx.doi.org/10.1155/2017/3408795
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AT mohamedbarakat seizureandpulmonaryembolismadifferentialthatcansavealife
AT dennisgenin seizureandpulmonaryembolismadifferentialthatcansavealife