Optical Coherence Tomography Noise Reduction Using Anisotropic Local Bivariate Gaussian Mixture Prior in 3D Complex Wavelet Domain

In this paper, MMSE estimator is employed for noise-free 3D OCT data recovery in 3D complex wavelet domain. Since the proposed distribution for noise-free data plays a key role in the performance of MMSE estimator, a priori distribution for the pdf of noise-free 3D complex wavelet coefficients is pr...

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Main Authors: Hossein Rabbani, Milan Sonka, Michael D. Abramoff
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:International Journal of Biomedical Imaging
Online Access:http://dx.doi.org/10.1155/2013/417491
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author Hossein Rabbani
Milan Sonka
Michael D. Abramoff
author_facet Hossein Rabbani
Milan Sonka
Michael D. Abramoff
author_sort Hossein Rabbani
collection DOAJ
description In this paper, MMSE estimator is employed for noise-free 3D OCT data recovery in 3D complex wavelet domain. Since the proposed distribution for noise-free data plays a key role in the performance of MMSE estimator, a priori distribution for the pdf of noise-free 3D complex wavelet coefficients is proposed which is able to model the main statistical properties of wavelets. We model the coefficients with a mixture of two bivariate Gaussian pdfs with local parameters which are able to capture the heavy-tailed property and inter- and intrascale dependencies of coefficients. In addition, based on the special structure of OCT images, we use an anisotropic windowing procedure for local parameters estimation that results in visual quality improvement. On this base, several OCT despeckling algorithms are obtained based on using Gaussian/two-sided Rayleigh noise distribution and homomorphic/nonhomomorphic model. In order to evaluate the performance of the proposed algorithm, we use 156 selected ROIs from 650 × 512 × 128 OCT dataset in the presence of wet AMD pathology. Our simulations show that the best MMSE estimator using local bivariate mixture prior is for the nonhomomorphic model in the presence of Gaussian noise which results in an improvement of 7.8 ± 1.7 in CNR.
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institution Kabale University
issn 1687-4188
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spelling doaj-art-c932a4459afe455db1031959526414822025-02-03T05:50:54ZengWileyInternational Journal of Biomedical Imaging1687-41881687-41962013-01-01201310.1155/2013/417491417491Optical Coherence Tomography Noise Reduction Using Anisotropic Local Bivariate Gaussian Mixture Prior in 3D Complex Wavelet DomainHossein Rabbani0Milan Sonka1Michael D. Abramoff2Biomedical Engineering Department, Medical Image & Signal Processing Research Center, Isfahan University of Medical Sciences, Isfahan 81745, IranThe Iowa Institute for Biomedical Imaging, The University of Iowa, Iowa City, IA 52242, USAThe Iowa Institute for Biomedical Imaging, The University of Iowa, Iowa City, IA 52242, USAIn this paper, MMSE estimator is employed for noise-free 3D OCT data recovery in 3D complex wavelet domain. Since the proposed distribution for noise-free data plays a key role in the performance of MMSE estimator, a priori distribution for the pdf of noise-free 3D complex wavelet coefficients is proposed which is able to model the main statistical properties of wavelets. We model the coefficients with a mixture of two bivariate Gaussian pdfs with local parameters which are able to capture the heavy-tailed property and inter- and intrascale dependencies of coefficients. In addition, based on the special structure of OCT images, we use an anisotropic windowing procedure for local parameters estimation that results in visual quality improvement. On this base, several OCT despeckling algorithms are obtained based on using Gaussian/two-sided Rayleigh noise distribution and homomorphic/nonhomomorphic model. In order to evaluate the performance of the proposed algorithm, we use 156 selected ROIs from 650 × 512 × 128 OCT dataset in the presence of wet AMD pathology. Our simulations show that the best MMSE estimator using local bivariate mixture prior is for the nonhomomorphic model in the presence of Gaussian noise which results in an improvement of 7.8 ± 1.7 in CNR.http://dx.doi.org/10.1155/2013/417491
spellingShingle Hossein Rabbani
Milan Sonka
Michael D. Abramoff
Optical Coherence Tomography Noise Reduction Using Anisotropic Local Bivariate Gaussian Mixture Prior in 3D Complex Wavelet Domain
International Journal of Biomedical Imaging
title Optical Coherence Tomography Noise Reduction Using Anisotropic Local Bivariate Gaussian Mixture Prior in 3D Complex Wavelet Domain
title_full Optical Coherence Tomography Noise Reduction Using Anisotropic Local Bivariate Gaussian Mixture Prior in 3D Complex Wavelet Domain
title_fullStr Optical Coherence Tomography Noise Reduction Using Anisotropic Local Bivariate Gaussian Mixture Prior in 3D Complex Wavelet Domain
title_full_unstemmed Optical Coherence Tomography Noise Reduction Using Anisotropic Local Bivariate Gaussian Mixture Prior in 3D Complex Wavelet Domain
title_short Optical Coherence Tomography Noise Reduction Using Anisotropic Local Bivariate Gaussian Mixture Prior in 3D Complex Wavelet Domain
title_sort optical coherence tomography noise reduction using anisotropic local bivariate gaussian mixture prior in 3d complex wavelet domain
url http://dx.doi.org/10.1155/2013/417491
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AT michaeldabramoff opticalcoherencetomographynoisereductionusinganisotropiclocalbivariategaussianmixturepriorin3dcomplexwaveletdomain