Rapid enlargement of pulmonary benign metastasizing leiomyoma with fluid-containing cystic change: a case report
Abstract Background Pulmonary benign metastasizing leiomyoma (PBML) is a rare disease that can occur in women with a history of uterine leiomyoma. Despite its benign histological features, like a malignancy, leiomyomas can on rare occasion spread to the lung. Typically, PBML presents with asymptomat...
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| Format: | Article |
| Language: | English |
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Japan Surgical Society
2022-05-01
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| Series: | Surgical Case Reports |
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| Online Access: | https://doi.org/10.1186/s40792-022-01444-3 |
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| author | Takahiro Yanagihara Naohiro Kobayashi Tomoyuki Kawamura Shinji Kikuchi Yukinobu Goto Hideo Ichimura Yukio Sato |
| author_facet | Takahiro Yanagihara Naohiro Kobayashi Tomoyuki Kawamura Shinji Kikuchi Yukinobu Goto Hideo Ichimura Yukio Sato |
| author_sort | Takahiro Yanagihara |
| collection | DOAJ |
| description | Abstract Background Pulmonary benign metastasizing leiomyoma (PBML) is a rare disease that can occur in women with a history of uterine leiomyoma. Despite its benign histological features, like a malignancy, leiomyomas can on rare occasion spread to the lung. Typically, PBML presents with asymptomatic multiple solid lung nodules with slow tumor progression, following hysterectomy. Here, we present an atypical case with rapid enlargement of PBML with fluid-containing cystic change. Case presentation We experienced a case of a 49-year-old woman with bilateral lung nodules following hysterectomy. Two nodules in the right lung had cystic change with fluid in the tumors. Hormone therapy was initiated after surgical biopsy of the left lung confirmed a diagnosis of PBML. However, the cystic component of right upper lobe lesion enlarged rapidly over the following 7 months, and, considering the risk of malignant transformation or tumor rupture, right upper lobectomy was performed. Pathologically, the fluid-containing tumor was diagnosed as PBML. Conclusion Given the risk of rapid progression, we should carefully consider the surgical indications of fluid-containing PBML. |
| format | Article |
| id | doaj-art-c92a3d5824aa4d22a618d1daaca6e19b |
| institution | Kabale University |
| issn | 2198-7793 |
| language | English |
| publishDate | 2022-05-01 |
| publisher | Japan Surgical Society |
| record_format | Article |
| series | Surgical Case Reports |
| spelling | doaj-art-c92a3d5824aa4d22a618d1daaca6e19b2025-08-20T03:36:06ZengJapan Surgical SocietySurgical Case Reports2198-77932022-05-01811510.1186/s40792-022-01444-3Rapid enlargement of pulmonary benign metastasizing leiomyoma with fluid-containing cystic change: a case reportTakahiro Yanagihara0Naohiro Kobayashi1Tomoyuki Kawamura2Shinji Kikuchi3Yukinobu Goto4Hideo Ichimura5Yukio Sato6Department of Thoracic Surgery, Faculty of Medicine, University of TsukubaDepartment of Thoracic Surgery, Faculty of Medicine, University of TsukubaDepartment of Thoracic Surgery, Faculty of Medicine, University of TsukubaDepartment of Thoracic Surgery, Faculty of Medicine, University of TsukubaDepartment of Thoracic Surgery, Faculty of Medicine, University of TsukubaDepartment of Thoracic Surgery, Faculty of Medicine, University of TsukubaDepartment of Thoracic Surgery, Faculty of Medicine, University of TsukubaAbstract Background Pulmonary benign metastasizing leiomyoma (PBML) is a rare disease that can occur in women with a history of uterine leiomyoma. Despite its benign histological features, like a malignancy, leiomyomas can on rare occasion spread to the lung. Typically, PBML presents with asymptomatic multiple solid lung nodules with slow tumor progression, following hysterectomy. Here, we present an atypical case with rapid enlargement of PBML with fluid-containing cystic change. Case presentation We experienced a case of a 49-year-old woman with bilateral lung nodules following hysterectomy. Two nodules in the right lung had cystic change with fluid in the tumors. Hormone therapy was initiated after surgical biopsy of the left lung confirmed a diagnosis of PBML. However, the cystic component of right upper lobe lesion enlarged rapidly over the following 7 months, and, considering the risk of malignant transformation or tumor rupture, right upper lobectomy was performed. Pathologically, the fluid-containing tumor was diagnosed as PBML. Conclusion Given the risk of rapid progression, we should carefully consider the surgical indications of fluid-containing PBML.https://doi.org/10.1186/s40792-022-01444-3Pulmonary benign metastasizing leiomyomaBenign metastasizing leiomyomaLeiomyomaCystic changeFluid-containing cystPulmonary metastasis |
| spellingShingle | Takahiro Yanagihara Naohiro Kobayashi Tomoyuki Kawamura Shinji Kikuchi Yukinobu Goto Hideo Ichimura Yukio Sato Rapid enlargement of pulmonary benign metastasizing leiomyoma with fluid-containing cystic change: a case report Surgical Case Reports Pulmonary benign metastasizing leiomyoma Benign metastasizing leiomyoma Leiomyoma Cystic change Fluid-containing cyst Pulmonary metastasis |
| title | Rapid enlargement of pulmonary benign metastasizing leiomyoma with fluid-containing cystic change: a case report |
| title_full | Rapid enlargement of pulmonary benign metastasizing leiomyoma with fluid-containing cystic change: a case report |
| title_fullStr | Rapid enlargement of pulmonary benign metastasizing leiomyoma with fluid-containing cystic change: a case report |
| title_full_unstemmed | Rapid enlargement of pulmonary benign metastasizing leiomyoma with fluid-containing cystic change: a case report |
| title_short | Rapid enlargement of pulmonary benign metastasizing leiomyoma with fluid-containing cystic change: a case report |
| title_sort | rapid enlargement of pulmonary benign metastasizing leiomyoma with fluid containing cystic change a case report |
| topic | Pulmonary benign metastasizing leiomyoma Benign metastasizing leiomyoma Leiomyoma Cystic change Fluid-containing cyst Pulmonary metastasis |
| url | https://doi.org/10.1186/s40792-022-01444-3 |
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