Alzheimer's disease image classification based on enhanced residual attention network.

With the increasing number of patients with Alzheimer's Disease (AD), the demand for early diagnosis and intervention is becoming increasingly urgent. The traditional detection methods for Alzheimer's disease mainly rely on clinical symptoms, biomarkers, and imaging examinations. However,...

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Main Authors: Xiaoli Li, Bairui Gong, Xinfang Chen, Hui Li, Guoming Yuan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0317376
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author Xiaoli Li
Bairui Gong
Xinfang Chen
Hui Li
Guoming Yuan
author_facet Xiaoli Li
Bairui Gong
Xinfang Chen
Hui Li
Guoming Yuan
author_sort Xiaoli Li
collection DOAJ
description With the increasing number of patients with Alzheimer's Disease (AD), the demand for early diagnosis and intervention is becoming increasingly urgent. The traditional detection methods for Alzheimer's disease mainly rely on clinical symptoms, biomarkers, and imaging examinations. However, these methods have limitations in the early detection of Alzheimer's disease, such as strong subjectivity in diagnostic criteria, high detection costs, and high misdiagnosis rates. To address these issues, this study proposes a deep learning model to detect Alzheimer's disease; it is called Enhanced Residual Attention Network (ERAN) that can classify medical images. By combining residual learning, attention mechanism, and soft thresholding, the feature representation ability and classification accuracy of the model have been improved. The accuracy of the model in detecting Alzheimer's disease has reached 99.36%, with a loss rate of only 0.0264. The experimental results indicate that the Enhanced Residual Attention Network has achieved excellent performance on the Alzheimer's disease test dataset, providing strong support for the early diagnosis and treatment of Alzheimer's disease.
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institution Kabale University
issn 1932-6203
language English
publishDate 2025-01-01
publisher Public Library of Science (PLoS)
record_format Article
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spelling doaj-art-c9281f2d41fc443495018cba6f7533882025-02-05T05:32:01ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01201e031737610.1371/journal.pone.0317376Alzheimer's disease image classification based on enhanced residual attention network.Xiaoli LiBairui GongXinfang ChenHui LiGuoming YuanWith the increasing number of patients with Alzheimer's Disease (AD), the demand for early diagnosis and intervention is becoming increasingly urgent. The traditional detection methods for Alzheimer's disease mainly rely on clinical symptoms, biomarkers, and imaging examinations. However, these methods have limitations in the early detection of Alzheimer's disease, such as strong subjectivity in diagnostic criteria, high detection costs, and high misdiagnosis rates. To address these issues, this study proposes a deep learning model to detect Alzheimer's disease; it is called Enhanced Residual Attention Network (ERAN) that can classify medical images. By combining residual learning, attention mechanism, and soft thresholding, the feature representation ability and classification accuracy of the model have been improved. The accuracy of the model in detecting Alzheimer's disease has reached 99.36%, with a loss rate of only 0.0264. The experimental results indicate that the Enhanced Residual Attention Network has achieved excellent performance on the Alzheimer's disease test dataset, providing strong support for the early diagnosis and treatment of Alzheimer's disease.https://doi.org/10.1371/journal.pone.0317376
spellingShingle Xiaoli Li
Bairui Gong
Xinfang Chen
Hui Li
Guoming Yuan
Alzheimer's disease image classification based on enhanced residual attention network.
PLoS ONE
title Alzheimer's disease image classification based on enhanced residual attention network.
title_full Alzheimer's disease image classification based on enhanced residual attention network.
title_fullStr Alzheimer's disease image classification based on enhanced residual attention network.
title_full_unstemmed Alzheimer's disease image classification based on enhanced residual attention network.
title_short Alzheimer's disease image classification based on enhanced residual attention network.
title_sort alzheimer s disease image classification based on enhanced residual attention network
url https://doi.org/10.1371/journal.pone.0317376
work_keys_str_mv AT xiaolili alzheimersdiseaseimageclassificationbasedonenhancedresidualattentionnetwork
AT bairuigong alzheimersdiseaseimageclassificationbasedonenhancedresidualattentionnetwork
AT xinfangchen alzheimersdiseaseimageclassificationbasedonenhancedresidualattentionnetwork
AT huili alzheimersdiseaseimageclassificationbasedonenhancedresidualattentionnetwork
AT guomingyuan alzheimersdiseaseimageclassificationbasedonenhancedresidualattentionnetwork