The study of oncolytic viruses reproduction in organ cultures of human lymphoid tumors

Oncolytic viruses are promising agents for the treatment of various types of tumors, including malignant non-Hodgkin lymphomas. In order to identify the most effective candidates from a wide panel of non-pathogenic antitumor strains, a study was carried out of their ability to reproduce in short-ter...

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Main Authors: F. E. Babaeva, A. V. Lipatova, D. V. Kochetkov, P. M. Chumakov, S. K. Kravchenko
Format: Article
Language:Russian
Published: ABV-press 2019-12-01
Series:Онкогематология
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Online Access:https://oncohematology.abvpress.ru/ongm/article/view/387
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author F. E. Babaeva
A. V. Lipatova
D. V. Kochetkov
P. M. Chumakov
S. K. Kravchenko
author_facet F. E. Babaeva
A. V. Lipatova
D. V. Kochetkov
P. M. Chumakov
S. K. Kravchenko
author_sort F. E. Babaeva
collection DOAJ
description Oncolytic viruses are promising agents for the treatment of various types of tumors, including malignant non-Hodgkin lymphomas. In order to identify the most effective candidates from a wide panel of non-pathogenic antitumor strains, a study was carried out of their ability to reproduce in short-term cultures of lymphoid tumor cells. Also, tumor cell cultures were characterized in relation to the presence of specific viral receptors CD54, CD55, CD155 on their surface.
format Article
id doaj-art-c9124efabda94af7bc4baf122d83f649
institution Kabale University
issn 1818-8346
2413-4023
language Russian
publishDate 2019-12-01
publisher ABV-press
record_format Article
series Онкогематология
spelling doaj-art-c9124efabda94af7bc4baf122d83f6492025-08-20T04:00:13ZrusABV-pressОнкогематология1818-83462413-40232019-12-01144848910.17650/1818-8346-2019-14-4-84-89333The study of oncolytic viruses reproduction in organ cultures of human lymphoid tumorsF. E. Babaeva0A. V. Lipatova1D. V. Kochetkov2P. M. Chumakov3S. K. Kravchenko4National Research Center for Hematology, Ministry of Health of RussiaEngelhardt Institute of Molecular Biology, Russian Academy of SciencesEngelhardt Institute of Molecular Biology, Russian Academy of SciencesEngelhardt Institute of Molecular Biology, Russian Academy of SciencesNational Research Center for Hematology, Ministry of Health of RussiaOncolytic viruses are promising agents for the treatment of various types of tumors, including malignant non-Hodgkin lymphomas. In order to identify the most effective candidates from a wide panel of non-pathogenic antitumor strains, a study was carried out of their ability to reproduce in short-term cultures of lymphoid tumor cells. Also, tumor cell cultures were characterized in relation to the presence of specific viral receptors CD54, CD55, CD155 on their surface.https://oncohematology.abvpress.ru/ongm/article/view/387oncolytic viruseslymphomaschemotherapyimmunotherapycell cultures
spellingShingle F. E. Babaeva
A. V. Lipatova
D. V. Kochetkov
P. M. Chumakov
S. K. Kravchenko
The study of oncolytic viruses reproduction in organ cultures of human lymphoid tumors
Онкогематология
oncolytic viruses
lymphomas
chemotherapy
immunotherapy
cell cultures
title The study of oncolytic viruses reproduction in organ cultures of human lymphoid tumors
title_full The study of oncolytic viruses reproduction in organ cultures of human lymphoid tumors
title_fullStr The study of oncolytic viruses reproduction in organ cultures of human lymphoid tumors
title_full_unstemmed The study of oncolytic viruses reproduction in organ cultures of human lymphoid tumors
title_short The study of oncolytic viruses reproduction in organ cultures of human lymphoid tumors
title_sort study of oncolytic viruses reproduction in organ cultures of human lymphoid tumors
topic oncolytic viruses
lymphomas
chemotherapy
immunotherapy
cell cultures
url https://oncohematology.abvpress.ru/ongm/article/view/387
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