The DRUG UTILIZATION EVALUATION OF MACROLIDES IN ENT OUTPATIENT DEPARTMENT IN TEACHING HOSPITAL PUNJAB, PAKISTAN.

Background: A major danger to the health care system is the rise in antibiotic resistance. The aim of current Study is to evaluate the comparison defined daily dose (DDD) and prescribed daily dose (PDD) of macrolide and to evaluate the prescribing pattern of the drug, either it met the standards or...

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Main Authors: Misbah naz, Ali Hassan Gillani, Muhammad Arsalan Amjad, Muhammad Qamar uz zaman, Muhammad Hassan Akbar, Sharjeel Ahmed, Jamshaid Akbar, Sameer Ali
Format: Article
Language:English
Published: Superior University Lahore, Pakistan 2022-10-01
Series:International Journal of Pharmacy & Integrated Health Sciences
Subjects:
Online Access:https://ijpihs.pk/index.php/IJPIHS/article/view/50
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author Misbah naz
Ali Hassan Gillani
Muhammad Arsalan Amjad
Muhammad Qamar uz zaman
Muhammad Hassan Akbar
Sharjeel Ahmed
Jamshaid Akbar
Sameer Ali
author_facet Misbah naz
Ali Hassan Gillani
Muhammad Arsalan Amjad
Muhammad Qamar uz zaman
Muhammad Hassan Akbar
Sharjeel Ahmed
Jamshaid Akbar
Sameer Ali
author_sort Misbah naz
collection DOAJ
description Background: A major danger to the health care system is the rise in antibiotic resistance. The aim of current Study is to evaluate the comparison defined daily dose (DDD) and prescribed daily dose (PDD) of macrolide and to evaluate the prescribing pattern of the drug, either it met the standards or not. Methodology: Quantitative, retrospective study was carried out to measure the use of antibiotics specifically macrolide antibiotics in ENT outdoor department of teaching hospital Punjab, Pakistan. Study research from August 2021 to October 2021, the patient who was reported in OPD of ENT department during study period of 3 month retrospectively. Results: Total 438 prescriptions were collected and reviewed to evaluate the prescribing pattern of macrolides in outdoor patients of ENT department. Out of 438 prescriptions only in one prescription 10 antibiotics was prescribe (polypharmacy) and in 19(4.3%) prescriptions only one antibiotic is prescribed. Drug prescribed by their generic were 438(100). Encounter with antibiotics 95%. All drug were prescribed from essential drug list (EDL). Azithromycin was the most commonly prescribed drug in ENT department, followed by clarithromycin. Conclusion: Control bacterial resistance is become challenge to our health care system, major portion of our population is become resistance to majority classes of antibiotic if this practice will continue in future, it became difficult to control or treat infectious diseases. Irrational use of drugs, over prescribing of antibiotics and brand prescribing were observing during the study. Lack of knowledge and non-adherence to the prescribing indicators are the major factors that contribute towards the irrational drug prescribing that ultimately leads towards the antibiotics resistance.
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institution Kabale University
issn 2958-1656
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publishDate 2022-10-01
publisher Superior University Lahore, Pakistan
record_format Article
series International Journal of Pharmacy & Integrated Health Sciences
spelling doaj-art-c91068c3db5545349c046da0ccc234fb2025-08-20T03:28:44ZengSuperior University Lahore, PakistanInternational Journal of Pharmacy & Integrated Health Sciences2958-16562789-28402022-10-013210.56536/ijpihs.v3i2.50The DRUG UTILIZATION EVALUATION OF MACROLIDES IN ENT OUTPATIENT DEPARTMENT IN TEACHING HOSPITAL PUNJAB, PAKISTAN.Misbah naz0Ali Hassan Gillani1Muhammad Arsalan Amjad2Muhammad Qamar uz zaman3Muhammad Hassan Akbar4Sharjeel Ahmed5Jamshaid Akbar6Sameer Ali7Chaudhry Muhammad Akram teaching and research hospital Lahore, pakistanDepartment of Pharmacy Administration and clinical Pharmacy, School of Pharmacy Xi’an Jatong University, Xi’an Shaanxi, ChinaDepartment of pharmaceutical Sciences superior university lahoreDepartment of Pharmacy, the Islamia University of Bahawalpur,Bahawalpur pakistanSchool of physiotherapy King Edward Medical University, Mayo hospital Lahore, PakistanClinical reasearch associate metrics reasearch private limited,PakistanDepartment of Pharmacy, the Islamia University of Bahawalpur,Bahawalpur pakistanChaudhry Muhammad Akram teaching and research hospital Lahore, pakistan Background: A major danger to the health care system is the rise in antibiotic resistance. The aim of current Study is to evaluate the comparison defined daily dose (DDD) and prescribed daily dose (PDD) of macrolide and to evaluate the prescribing pattern of the drug, either it met the standards or not. Methodology: Quantitative, retrospective study was carried out to measure the use of antibiotics specifically macrolide antibiotics in ENT outdoor department of teaching hospital Punjab, Pakistan. Study research from August 2021 to October 2021, the patient who was reported in OPD of ENT department during study period of 3 month retrospectively. Results: Total 438 prescriptions were collected and reviewed to evaluate the prescribing pattern of macrolides in outdoor patients of ENT department. Out of 438 prescriptions only in one prescription 10 antibiotics was prescribe (polypharmacy) and in 19(4.3%) prescriptions only one antibiotic is prescribed. Drug prescribed by their generic were 438(100). Encounter with antibiotics 95%. All drug were prescribed from essential drug list (EDL). Azithromycin was the most commonly prescribed drug in ENT department, followed by clarithromycin. Conclusion: Control bacterial resistance is become challenge to our health care system, major portion of our population is become resistance to majority classes of antibiotic if this practice will continue in future, it became difficult to control or treat infectious diseases. Irrational use of drugs, over prescribing of antibiotics and brand prescribing were observing during the study. Lack of knowledge and non-adherence to the prescribing indicators are the major factors that contribute towards the irrational drug prescribing that ultimately leads towards the antibiotics resistance. https://ijpihs.pk/index.php/IJPIHS/article/view/50Antibiotics resistanceClarithromycindefined daily doseprescribed dosemacrolideazithromycin
spellingShingle Misbah naz
Ali Hassan Gillani
Muhammad Arsalan Amjad
Muhammad Qamar uz zaman
Muhammad Hassan Akbar
Sharjeel Ahmed
Jamshaid Akbar
Sameer Ali
The DRUG UTILIZATION EVALUATION OF MACROLIDES IN ENT OUTPATIENT DEPARTMENT IN TEACHING HOSPITAL PUNJAB, PAKISTAN.
International Journal of Pharmacy & Integrated Health Sciences
Antibiotics resistance
Clarithromycin
defined daily dose
prescribed dose
macrolide
azithromycin
title The DRUG UTILIZATION EVALUATION OF MACROLIDES IN ENT OUTPATIENT DEPARTMENT IN TEACHING HOSPITAL PUNJAB, PAKISTAN.
title_full The DRUG UTILIZATION EVALUATION OF MACROLIDES IN ENT OUTPATIENT DEPARTMENT IN TEACHING HOSPITAL PUNJAB, PAKISTAN.
title_fullStr The DRUG UTILIZATION EVALUATION OF MACROLIDES IN ENT OUTPATIENT DEPARTMENT IN TEACHING HOSPITAL PUNJAB, PAKISTAN.
title_full_unstemmed The DRUG UTILIZATION EVALUATION OF MACROLIDES IN ENT OUTPATIENT DEPARTMENT IN TEACHING HOSPITAL PUNJAB, PAKISTAN.
title_short The DRUG UTILIZATION EVALUATION OF MACROLIDES IN ENT OUTPATIENT DEPARTMENT IN TEACHING HOSPITAL PUNJAB, PAKISTAN.
title_sort drug utilization evaluation of macrolides in ent outpatient department in teaching hospital punjab pakistan
topic Antibiotics resistance
Clarithromycin
defined daily dose
prescribed dose
macrolide
azithromycin
url https://ijpihs.pk/index.php/IJPIHS/article/view/50
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