Suicide attempts in elderly Han Chinese patients with major depressive disorder: prevalence and associated factors
Objective: Suicide attempts (SA) are common in elderly patients with major depressive disorder (MDD), but few studies have focused on the prevalence and associated factors in elderly Chinese Han patients with MDD. Method: A total of 266 first episode and drug naïve older patients with MDD (age ≥ 50 ...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-09-01
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| Series: | Acta Psychologica |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0001691825005414 |
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| author | Xiaofan Zhou Yu Zhou Xiang Yang Zhang |
| author_facet | Xiaofan Zhou Yu Zhou Xiang Yang Zhang |
| author_sort | Xiaofan Zhou |
| collection | DOAJ |
| description | Objective: Suicide attempts (SA) are common in elderly patients with major depressive disorder (MDD), but few studies have focused on the prevalence and associated factors in elderly Chinese Han patients with MDD. Method: A total of 266 first episode and drug naïve older patients with MDD (age ≥ 50 years) were recruited. We measured depressive symptoms, anxiety symptoms and psychotic symptoms by the Hamilton Depression Rating Scale (HAMD), the Hamilton Anxiety Rating Scale (HAMA), the positive subscale of the Positive and Negative Syndrome Scale (PANSS) and the Clinical General Impression Inventory (CGIS). Fasting serum samples were collected to measure thyroid hormone levels and metabolic parameters. Results: The prevalence of SA was 24.4 %. Patients with SA had higher HAMD, HAMA, PANSS positive subscale and CGI-S scores, as well as higher levels of TSH, TgAb, TPOAb, FBG, TC, LDL-C, TG, and systolic and diastolic blood pressure. Logistic regression analysis showed that suicide attempts were correlated with HAMA score, CGI-S score and TC levels in elderly patients with MDD. Conclusions: The findings show a high prevalence of suicide attempts in elderly patients with MDD. In elderly patients with MDD, severity of anxiety, CGI-S score and TC levels were associated factors for suicide attempts. |
| format | Article |
| id | doaj-art-c90d588fb2f548d1b4496da45b0b4594 |
| institution | Kabale University |
| issn | 0001-6918 |
| language | English |
| publishDate | 2025-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Acta Psychologica |
| spelling | doaj-art-c90d588fb2f548d1b4496da45b0b45942025-08-20T03:55:53ZengElsevierActa Psychologica0001-69182025-09-0125910522810.1016/j.actpsy.2025.105228Suicide attempts in elderly Han Chinese patients with major depressive disorder: prevalence and associated factorsXiaofan Zhou0Yu Zhou1Xiang Yang Zhang2CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, ChinaInstitute of Psychology, Shandong Second Medical University, Weifang, ChinaCAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China; Corresponding author at: CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, 16 Lincui Road, Chaoyang District, Beijing 100101, China.Objective: Suicide attempts (SA) are common in elderly patients with major depressive disorder (MDD), but few studies have focused on the prevalence and associated factors in elderly Chinese Han patients with MDD. Method: A total of 266 first episode and drug naïve older patients with MDD (age ≥ 50 years) were recruited. We measured depressive symptoms, anxiety symptoms and psychotic symptoms by the Hamilton Depression Rating Scale (HAMD), the Hamilton Anxiety Rating Scale (HAMA), the positive subscale of the Positive and Negative Syndrome Scale (PANSS) and the Clinical General Impression Inventory (CGIS). Fasting serum samples were collected to measure thyroid hormone levels and metabolic parameters. Results: The prevalence of SA was 24.4 %. Patients with SA had higher HAMD, HAMA, PANSS positive subscale and CGI-S scores, as well as higher levels of TSH, TgAb, TPOAb, FBG, TC, LDL-C, TG, and systolic and diastolic blood pressure. Logistic regression analysis showed that suicide attempts were correlated with HAMA score, CGI-S score and TC levels in elderly patients with MDD. Conclusions: The findings show a high prevalence of suicide attempts in elderly patients with MDD. In elderly patients with MDD, severity of anxiety, CGI-S score and TC levels were associated factors for suicide attempts.http://www.sciencedirect.com/science/article/pii/S0001691825005414Major depressive disorderSuicide attemptsElderly patients |
| spellingShingle | Xiaofan Zhou Yu Zhou Xiang Yang Zhang Suicide attempts in elderly Han Chinese patients with major depressive disorder: prevalence and associated factors Acta Psychologica Major depressive disorder Suicide attempts Elderly patients |
| title | Suicide attempts in elderly Han Chinese patients with major depressive disorder: prevalence and associated factors |
| title_full | Suicide attempts in elderly Han Chinese patients with major depressive disorder: prevalence and associated factors |
| title_fullStr | Suicide attempts in elderly Han Chinese patients with major depressive disorder: prevalence and associated factors |
| title_full_unstemmed | Suicide attempts in elderly Han Chinese patients with major depressive disorder: prevalence and associated factors |
| title_short | Suicide attempts in elderly Han Chinese patients with major depressive disorder: prevalence and associated factors |
| title_sort | suicide attempts in elderly han chinese patients with major depressive disorder prevalence and associated factors |
| topic | Major depressive disorder Suicide attempts Elderly patients |
| url | http://www.sciencedirect.com/science/article/pii/S0001691825005414 |
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