Backsplicing of the HIV-1 transcript generates multiple circRNAs to promote viral replication
Abstract Circular RNAs (circRNAs) are a family of non-coding RNAs that originate from a non-canonical splicing event (backsplicing) that forms covalently closed continuous loops. An analysis of the human immunodeficiency type 1 virus (HIV-1) complex splicing pattern indicated that the virus had the...
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| Main Authors: | Christopher Mauer, Sean Paz, Massimo Caputi |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-03-01
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| Series: | npj Viruses |
| Online Access: | https://doi.org/10.1038/s44298-025-00105-0 |
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