Bovine lactoferrin drives cell cycle arrest and alters the transcriptomic profile of NSCLC cells

Bovine lactoferrin drives cell cycle arrest and alters the transcriptomic profile of NSCLC cells

Abstract Non-small cell lung cancer (NSCLC) accounts for approximately 80–85% of all lung cancer cases. NSCLC is less sensitive to conventional chemotherapeutic agents, and high mortality and recurrence rates have become the impetus to find alternative therapies. Bovine lactoferrin (bLF) derived fro...

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Bibliographic Details
Main Authors: Jinxian Su, Yu Zhao, Mengtian Li, Guoxin Chen, Chun Liu, Adi Idris, Zhongren Ma, Haixia Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Lung cancer
Bovine lactoferrin
Cell proliferation
Cell cycle
Cell apoptosis
Online Access:https://doi.org/10.1038/s41598-025-13796-5
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