Dispersive Liquid–Liquid Microextraction Method Utilizing a Novel Peripherally Tetra-Substituted Ni(II) Phthalocyanine as a Sensor Prior to UV-Visible Spectrophotometry for the Determination of Co<sup>2+</sup>
Dispersive liquid–liquid microextraction (DLLME) is an economical, rapid, sensitive, and environmentally friendly miniaturized liquid–liquid extraction format. It has been successfully applied in trace element analysis since 2006 when it was first proposed. This article describes a new dispersive li...
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2025-06-01
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| author | Yasemin Çağlar Ece Tuğba Saka |
| author_facet | Yasemin Çağlar Ece Tuğba Saka |
| author_sort | Yasemin Çağlar |
| collection | DOAJ |
| description | Dispersive liquid–liquid microextraction (DLLME) is an economical, rapid, sensitive, and environmentally friendly miniaturized liquid–liquid extraction format. It has been successfully applied in trace element analysis since 2006 when it was first proposed. This article describes a new dispersive liquid–liquid microextraction method for the determination of trace amounts of Co<sup>2+</sup>. In brief, this method involves the extraction of Co<sup>2+</sup> from the sample to the trichloromethane phase by the dispersive action of methanol after the formation of a complex with a novel 9-(methylaminomethyl)anthracene-Ni(II) phthalocyanine (MAMA Ni(II)Pc <b>2</b>) as a sensor. The first step in this study was the synthesis and characterisation of the sensor. Later, the proposed method was optimized with respect to various parameters such as extraction and dispersive solvents and their amounts, pH, sensor concentration, and centrifugation time and rate. The calibration graph was linear between 0.40 and 260 µg/L, with an R<sup>2</sup> of 0.9978. The limit of detection and limit of quantification were found to be 0.19 µg/L and 0.46 µg/L, respectively. To evaluate the precision of this method, the analysis of a 50 µg/L Co<sup>2+</sup> solution was carried out. The intra-day and inter-day relative standard deviation values were calculated as 1.7% and 2.4%, respectively (n = 7). The accuracy of the proposed method was investigated by means of a standard addition/recovery test. |
| format | Article |
| id | doaj-art-c903a317dc1643e486af70c3a0e71b40 |
| institution | OA Journals |
| issn | 1420-3049 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | MDPI AG |
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| series | Molecules |
| spelling | doaj-art-c903a317dc1643e486af70c3a0e71b402025-08-20T02:20:59ZengMDPI AGMolecules1420-30492025-06-013012254810.3390/molecules30122548Dispersive Liquid–Liquid Microextraction Method Utilizing a Novel Peripherally Tetra-Substituted Ni(II) Phthalocyanine as a Sensor Prior to UV-Visible Spectrophotometry for the Determination of Co<sup>2+</sup>Yasemin Çağlar0Ece Tuğba Saka1Department of Genetic and Bioengineering, Giresun University, Giresun 28200, TürkiyeDepartment of Chemistry, Karadeniz Technical University, Trabzon 61080, TürkiyeDispersive liquid–liquid microextraction (DLLME) is an economical, rapid, sensitive, and environmentally friendly miniaturized liquid–liquid extraction format. It has been successfully applied in trace element analysis since 2006 when it was first proposed. This article describes a new dispersive liquid–liquid microextraction method for the determination of trace amounts of Co<sup>2+</sup>. In brief, this method involves the extraction of Co<sup>2+</sup> from the sample to the trichloromethane phase by the dispersive action of methanol after the formation of a complex with a novel 9-(methylaminomethyl)anthracene-Ni(II) phthalocyanine (MAMA Ni(II)Pc <b>2</b>) as a sensor. The first step in this study was the synthesis and characterisation of the sensor. Later, the proposed method was optimized with respect to various parameters such as extraction and dispersive solvents and their amounts, pH, sensor concentration, and centrifugation time and rate. The calibration graph was linear between 0.40 and 260 µg/L, with an R<sup>2</sup> of 0.9978. The limit of detection and limit of quantification were found to be 0.19 µg/L and 0.46 µg/L, respectively. To evaluate the precision of this method, the analysis of a 50 µg/L Co<sup>2+</sup> solution was carried out. The intra-day and inter-day relative standard deviation values were calculated as 1.7% and 2.4%, respectively (n = 7). The accuracy of the proposed method was investigated by means of a standard addition/recovery test.https://www.mdpi.com/1420-3049/30/12/2548DLLMEphthalocyanineCo<sup>2+</sup>anthracene |
| spellingShingle | Yasemin Çağlar Ece Tuğba Saka Dispersive Liquid–Liquid Microextraction Method Utilizing a Novel Peripherally Tetra-Substituted Ni(II) Phthalocyanine as a Sensor Prior to UV-Visible Spectrophotometry for the Determination of Co<sup>2+</sup> Molecules DLLME phthalocyanine Co<sup>2+</sup> anthracene |
| title | Dispersive Liquid–Liquid Microextraction Method Utilizing a Novel Peripherally Tetra-Substituted Ni(II) Phthalocyanine as a Sensor Prior to UV-Visible Spectrophotometry for the Determination of Co<sup>2+</sup> |
| title_full | Dispersive Liquid–Liquid Microextraction Method Utilizing a Novel Peripherally Tetra-Substituted Ni(II) Phthalocyanine as a Sensor Prior to UV-Visible Spectrophotometry for the Determination of Co<sup>2+</sup> |
| title_fullStr | Dispersive Liquid–Liquid Microextraction Method Utilizing a Novel Peripherally Tetra-Substituted Ni(II) Phthalocyanine as a Sensor Prior to UV-Visible Spectrophotometry for the Determination of Co<sup>2+</sup> |
| title_full_unstemmed | Dispersive Liquid–Liquid Microextraction Method Utilizing a Novel Peripherally Tetra-Substituted Ni(II) Phthalocyanine as a Sensor Prior to UV-Visible Spectrophotometry for the Determination of Co<sup>2+</sup> |
| title_short | Dispersive Liquid–Liquid Microextraction Method Utilizing a Novel Peripherally Tetra-Substituted Ni(II) Phthalocyanine as a Sensor Prior to UV-Visible Spectrophotometry for the Determination of Co<sup>2+</sup> |
| title_sort | dispersive liquid liquid microextraction method utilizing a novel peripherally tetra substituted ni ii phthalocyanine as a sensor prior to uv visible spectrophotometry for the determination of co sup 2 sup |
| topic | DLLME phthalocyanine Co<sup>2+</sup> anthracene |
| url | https://www.mdpi.com/1420-3049/30/12/2548 |
| work_keys_str_mv | AT yasemincaglar dispersiveliquidliquidmicroextractionmethodutilizinganovelperipherallytetrasubstitutedniiiphthalocyanineasasensorpriortouvvisiblespectrophotometryforthedeterminationofcosup2sup AT ecetugbasaka dispersiveliquidliquidmicroextractionmethodutilizinganovelperipherallytetrasubstitutedniiiphthalocyanineasasensorpriortouvvisiblespectrophotometryforthedeterminationofcosup2sup |