Effects of Graphene Quantum Dots on Renal Fibrosis Through Alleviating Oxidative Stress and Restoring Mitochondrial Membrane Potential

Effects of Graphene Quantum Dots on Renal Fibrosis Through Alleviating Oxidative Stress and Restoring Mitochondrial Membrane Potential

Abstract Podocyte injury and proteinuria in glomerular disease are critical indicators of acute kidney injury progression to chronic kidney disease. Renal mitochondrial dysfunction, mediated by intracellular calcium levels and oxidative stress, is a major contributor to podocyte complications. Despi...

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Main Authors: Kyu Hong Kim, Jong Bo Park, Jung Nam An, Gaeun Bae, Kyu Hyeon Kim, Seong Joon Park, Youngjin Jung, Yong Chul Kim, Jung Pyo Lee, Jae Wook Lee, Dong Ki Kim, Yon Su Kim, Byung Hee Hong, Seung Hee Yang
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Advanced Science
Subjects:
TRPC5
graphene quantum dots
mitochondrial membrane potential
oxidative stress
renal fibrosis
Online Access:https://doi.org/10.1002/advs.202410747
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