Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp
Mullerian adenosarcoma of the cervix is a rare tumor composed of benign epithelial and malignant stromal components. Sarcomatous overgrowth and heterologous elements in cervical adenosarcoma are extremely infrequent. We report the case of a 26-year-old woman admitted at the gynaecology department fo...
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Wiley
2012-01-01
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Series: | Case Reports in Obstetrics and Gynecology |
Online Access: | http://dx.doi.org/10.1155/2012/358302 |
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author | Slim Charfi Rim Kallel Hela Mnif Sameh Ellouze Mohamed Dhouib Mohamed Guermazi Abdelmajid Khabir Tahya Sellami-Boudawara |
author_facet | Slim Charfi Rim Kallel Hela Mnif Sameh Ellouze Mohamed Dhouib Mohamed Guermazi Abdelmajid Khabir Tahya Sellami-Boudawara |
author_sort | Slim Charfi |
collection | DOAJ |
description | Mullerian adenosarcoma of the cervix is a rare tumor composed of benign epithelial and malignant stromal components. Sarcomatous overgrowth and heterologous elements in cervical adenosarcoma are extremely infrequent. We report the case of a 26-year-old woman admitted at the gynaecology department for a painless mass protruding from her vagina. The initial pathological exam concluded to endocervical polyp. Six months later, the patient was readmitted with a recurrence of the polyp. The pathological exam demonstrated interlacing fascicles of elongated spindle cells with few mitotic activity and no glandular formation. After reviewing of the initial polyp the diagnosis of mullerian adenosarcoma was suggested. A second recurrence of the polyp was noted one month later. Histopathological exam of the recurrent polyp confirmed the diagnosis of adenosarcoma with sarcomatous overgrowth and heterologous elements. The patient was lost for follow-up. Cervical adenosarcoma with sarcomatous overgrowth and heterologous element is a rare tumor that occurs in younger age in contrast to endometrium/corpus uterin mullerian adenosarcoma. In young women with recurrent cervical polyp, mullerian adenosarcoma must be considered and should be excluded by careful histopathological exam. Sarcomatous overgrowth and myometrial invasion are the most important prognostic factors. Treatment strategy is still unclear. |
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id | doaj-art-c8f33776c3134b9a8e4a47bc74836b3e |
institution | Kabale University |
issn | 2090-6684 2090-6692 |
language | English |
publishDate | 2012-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Obstetrics and Gynecology |
spelling | doaj-art-c8f33776c3134b9a8e4a47bc74836b3e2025-02-03T01:10:29ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922012-01-01201210.1155/2012/358302358302Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical PolypSlim Charfi0Rim Kallel1Hela Mnif2Sameh Ellouze3Mohamed Dhouib4Mohamed Guermazi5Abdelmajid Khabir6Tahya Sellami-Boudawara7Laboratoire D’anatomie et de Cytologie Pathologiques, Department of Pathology, CHU Habib Bourguiba, 3029 Sfax, TunisiaLaboratoire D’anatomie et de Cytologie Pathologiques, Department of Pathology, CHU Habib Bourguiba, 3029 Sfax, TunisiaLaboratoire D’anatomie et de Cytologie Pathologiques, Department of Pathology, CHU Habib Bourguiba, 3029 Sfax, TunisiaLaboratoire D’anatomie et de Cytologie Pathologiques, Department of Pathology, CHU Habib Bourguiba, 3029 Sfax, TunisiaDepartment of Gynaecology and Obstetrics, CHU Hedi Chaker, 3029 Sfax, TunisiaDepartment of Gynaecology and Obstetrics, CHU Hedi Chaker, 3029 Sfax, TunisiaLaboratoire D’anatomie et de Cytologie Pathologiques, Department of Pathology, CHU Habib Bourguiba, 3029 Sfax, TunisiaLaboratoire D’anatomie et de Cytologie Pathologiques, Department of Pathology, CHU Habib Bourguiba, 3029 Sfax, TunisiaMullerian adenosarcoma of the cervix is a rare tumor composed of benign epithelial and malignant stromal components. Sarcomatous overgrowth and heterologous elements in cervical adenosarcoma are extremely infrequent. We report the case of a 26-year-old woman admitted at the gynaecology department for a painless mass protruding from her vagina. The initial pathological exam concluded to endocervical polyp. Six months later, the patient was readmitted with a recurrence of the polyp. The pathological exam demonstrated interlacing fascicles of elongated spindle cells with few mitotic activity and no glandular formation. After reviewing of the initial polyp the diagnosis of mullerian adenosarcoma was suggested. A second recurrence of the polyp was noted one month later. Histopathological exam of the recurrent polyp confirmed the diagnosis of adenosarcoma with sarcomatous overgrowth and heterologous elements. The patient was lost for follow-up. Cervical adenosarcoma with sarcomatous overgrowth and heterologous element is a rare tumor that occurs in younger age in contrast to endometrium/corpus uterin mullerian adenosarcoma. In young women with recurrent cervical polyp, mullerian adenosarcoma must be considered and should be excluded by careful histopathological exam. Sarcomatous overgrowth and myometrial invasion are the most important prognostic factors. Treatment strategy is still unclear.http://dx.doi.org/10.1155/2012/358302 |
spellingShingle | Slim Charfi Rim Kallel Hela Mnif Sameh Ellouze Mohamed Dhouib Mohamed Guermazi Abdelmajid Khabir Tahya Sellami-Boudawara Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp Case Reports in Obstetrics and Gynecology |
title | Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp |
title_full | Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp |
title_fullStr | Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp |
title_full_unstemmed | Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp |
title_short | Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp |
title_sort | mullerian adenosaroma of the cervix with sarcomatous overgrowth and heterologous elements presenting as a recurrent cervical polyp |
url | http://dx.doi.org/10.1155/2012/358302 |
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