δ-Catenin is genetically and biologically associated with cortical cataract and future Alzheimer-related structural and functional brain changes.

δ-Catenin is genetically and biologically associated with cortical cataract and future Alzheimer-related structural and functional brain changes.

Multiple lines of evidence suggest that specific subtypes of age-related cataract (ARC) and Alzheimer disease (AD) are related etiologically. To identify shared genetic factors for ARC and AD, we estimated co-heritability of quantitative measures of cataract subtypes with AD-related brain MRI traits...

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Main Authors: Gyungah Jun, Juliet A Moncaster, Carolina Koutras, Sudha Seshadri, Jacqueline Buros, Ann C McKee, Georges Levesque, Philip A Wolf, Peter St George-Hyslop, Lee E Goldstein, Lindsay A Farrer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0043728&type=printable
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