Feasibility of Radial Endobronchial Ultrasound-Guided Bronchoscopic Cryobiopsy without Fluoroscopy for Lung Parenchymal Lesions

Background. Cryobiopsy is used to biopsy peripheral lung lesions through flexible bronchoscopy with fluoroscopic guidance. However, fluoroscopy is not available at some institutions. This study evaluated the feasibility of radial endobronchial ultrasound-guided bronchoscopic cryobiopsy without fluor...

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Main Authors: Chih-Hao Chang, Chung-Shu Lee, Shih-Hong Li, Fu-Tsai Chung, Chih-Wei Wang, Yu-Hsiang Juan, Han-Chung Hu, Li-Fu Li, Ning-Hung Chen, Cheng-Ta Yang, Kuo-Chin Kao
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2017/7170687
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author Chih-Hao Chang
Chung-Shu Lee
Shih-Hong Li
Fu-Tsai Chung
Chih-Wei Wang
Yu-Hsiang Juan
Han-Chung Hu
Li-Fu Li
Ning-Hung Chen
Cheng-Ta Yang
Kuo-Chin Kao
author_facet Chih-Hao Chang
Chung-Shu Lee
Shih-Hong Li
Fu-Tsai Chung
Chih-Wei Wang
Yu-Hsiang Juan
Han-Chung Hu
Li-Fu Li
Ning-Hung Chen
Cheng-Ta Yang
Kuo-Chin Kao
author_sort Chih-Hao Chang
collection DOAJ
description Background. Cryobiopsy is used to biopsy peripheral lung lesions through flexible bronchoscopy with fluoroscopic guidance. However, fluoroscopy is not available at some institutions. This study evaluated the feasibility of radial endobronchial ultrasound-guided bronchoscopic cryobiopsy without fluoroscopy. Methods. This retrospective study was conducted at Chang Gung Memorial Hospital, Linkou branch, in Taiwan. This study enrolled patients who received bronchoscopy examinations with cryotechnology between July 2014 and June 2016. The data were collected through medical chart review. Results. During the study period, 101 patients underwent bronchoscopy examinations with cryotechnology. Ninety patients with endobronchial tumors were excluded from this study. Eleven patients who underwent radial endobronchial ultrasound-guided bronchoscopic cryobiopsy for lung parenchymal lesions were enrolled into this study. The mean age was 61.1 ± 13.8 years. Five patients were men, and the other six were women. The number of cryobiopsies ranged from 1 to 3. In the histological biopsies, the mean specimen diameter was 0.53 ± 0.23 cm, and the mean biopsy area was 0.20 ± 0.19 cm2. Nine of 11 patients had pathological diagnoses. No complications, including pneumothorax, respiratory failure, or major bleeding, were recorded after the procedure. Conclusions. Endobronchial ultrasound is used to ensure biopsy location, and endobronchial ultrasound-guided cryobiopsy is a feasible technique to biopsy peripheral lung lesions in selected cases at institutions without fluoroscopy equipment. This study provided some rationale for further studies examining the impact of fluoroscopy.
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spelling doaj-art-c8ef46c5cd534f5f8a8d35446048a1842025-08-20T02:19:41ZengWileyCanadian Respiratory Journal1198-22411916-72452017-01-01201710.1155/2017/71706877170687Feasibility of Radial Endobronchial Ultrasound-Guided Bronchoscopic Cryobiopsy without Fluoroscopy for Lung Parenchymal LesionsChih-Hao Chang0Chung-Shu Lee1Shih-Hong Li2Fu-Tsai Chung3Chih-Wei Wang4Yu-Hsiang Juan5Han-Chung Hu6Li-Fu Li7Ning-Hung Chen8Cheng-Ta Yang9Kuo-Chin Kao10Department of Pulmonary and Critical Care Medicine, Linkou Chang Gung Memorial Hospital, and Chang Gung University, Taoyuan, TaiwanDepartment of Pulmonary and Critical Care Medicine, Linkou Chang Gung Memorial Hospital, and Chang Gung University, Taoyuan, TaiwanDepartment of Pulmonary and Critical Care Medicine, Linkou Chang Gung Memorial Hospital, and Chang Gung University, Taoyuan, TaiwanDepartment of Pulmonary and Critical Care Medicine, Linkou Chang Gung Memorial Hospital, and Chang Gung University, Taoyuan, TaiwanDepartment of Pathology, Linkou Chang Gung Memorial Hospital, TaiwanDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Linkou and Chang Gung University, Taoyuan, TaiwanDepartment of Pulmonary and Critical Care Medicine, Linkou Chang Gung Memorial Hospital, and Chang Gung University, Taoyuan, TaiwanDepartment of Pulmonary and Critical Care Medicine, Linkou Chang Gung Memorial Hospital, and Chang Gung University, Taoyuan, TaiwanDepartment of Pulmonary and Critical Care Medicine, Linkou Chang Gung Memorial Hospital, and Chang Gung University, Taoyuan, TaiwanDepartment of Pulmonary and Critical Care Medicine, Linkou Chang Gung Memorial Hospital, and Chang Gung University, Taoyuan, TaiwanDepartment of Pulmonary and Critical Care Medicine, Linkou Chang Gung Memorial Hospital, and Chang Gung University, Taoyuan, TaiwanBackground. Cryobiopsy is used to biopsy peripheral lung lesions through flexible bronchoscopy with fluoroscopic guidance. However, fluoroscopy is not available at some institutions. This study evaluated the feasibility of radial endobronchial ultrasound-guided bronchoscopic cryobiopsy without fluoroscopy. Methods. This retrospective study was conducted at Chang Gung Memorial Hospital, Linkou branch, in Taiwan. This study enrolled patients who received bronchoscopy examinations with cryotechnology between July 2014 and June 2016. The data were collected through medical chart review. Results. During the study period, 101 patients underwent bronchoscopy examinations with cryotechnology. Ninety patients with endobronchial tumors were excluded from this study. Eleven patients who underwent radial endobronchial ultrasound-guided bronchoscopic cryobiopsy for lung parenchymal lesions were enrolled into this study. The mean age was 61.1 ± 13.8 years. Five patients were men, and the other six were women. The number of cryobiopsies ranged from 1 to 3. In the histological biopsies, the mean specimen diameter was 0.53 ± 0.23 cm, and the mean biopsy area was 0.20 ± 0.19 cm2. Nine of 11 patients had pathological diagnoses. No complications, including pneumothorax, respiratory failure, or major bleeding, were recorded after the procedure. Conclusions. Endobronchial ultrasound is used to ensure biopsy location, and endobronchial ultrasound-guided cryobiopsy is a feasible technique to biopsy peripheral lung lesions in selected cases at institutions without fluoroscopy equipment. This study provided some rationale for further studies examining the impact of fluoroscopy.http://dx.doi.org/10.1155/2017/7170687
spellingShingle Chih-Hao Chang
Chung-Shu Lee
Shih-Hong Li
Fu-Tsai Chung
Chih-Wei Wang
Yu-Hsiang Juan
Han-Chung Hu
Li-Fu Li
Ning-Hung Chen
Cheng-Ta Yang
Kuo-Chin Kao
Feasibility of Radial Endobronchial Ultrasound-Guided Bronchoscopic Cryobiopsy without Fluoroscopy for Lung Parenchymal Lesions
Canadian Respiratory Journal
title Feasibility of Radial Endobronchial Ultrasound-Guided Bronchoscopic Cryobiopsy without Fluoroscopy for Lung Parenchymal Lesions
title_full Feasibility of Radial Endobronchial Ultrasound-Guided Bronchoscopic Cryobiopsy without Fluoroscopy for Lung Parenchymal Lesions
title_fullStr Feasibility of Radial Endobronchial Ultrasound-Guided Bronchoscopic Cryobiopsy without Fluoroscopy for Lung Parenchymal Lesions
title_full_unstemmed Feasibility of Radial Endobronchial Ultrasound-Guided Bronchoscopic Cryobiopsy without Fluoroscopy for Lung Parenchymal Lesions
title_short Feasibility of Radial Endobronchial Ultrasound-Guided Bronchoscopic Cryobiopsy without Fluoroscopy for Lung Parenchymal Lesions
title_sort feasibility of radial endobronchial ultrasound guided bronchoscopic cryobiopsy without fluoroscopy for lung parenchymal lesions
url http://dx.doi.org/10.1155/2017/7170687
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