A novel eco-friendly Acinetobacter strain A1-4-2 for bioremediation of aquatic pollutants
Abstract The increasing accumulation of hydrocarbons and aromatic compounds in aquatic ecosystems, stemming from anthropogenic activities, poses severe ecological challenges, including disrupting biodiversity and threatening human health through the food chain. This study presents Acinetobacter stra...
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Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-025-05431-0 |
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| author | Rui Wang Jiahua Wang Ling Wang Yulun Cai Yuan Wang Huifang Luo Bing Chen Junlv Chen Jiasong Fang Zengfu Song |
| author_facet | Rui Wang Jiahua Wang Ling Wang Yulun Cai Yuan Wang Huifang Luo Bing Chen Junlv Chen Jiasong Fang Zengfu Song |
| author_sort | Rui Wang |
| collection | DOAJ |
| description | Abstract The increasing accumulation of hydrocarbons and aromatic compounds in aquatic ecosystems, stemming from anthropogenic activities, poses severe ecological challenges, including disrupting biodiversity and threatening human health through the food chain. This study presents Acinetobacter strain A1-4-2, isolated from a hairy crab farming base, which could represent a novel Acinetobacter species. The metagenomic analysis of approximately 12,000 publicly available datasets revealed that this novel Acinetobacter species is widely distributed across various environments, particularly in those with high organic matter content, such as sludge, feces, and wastewater. Strain A1-4-2 exhibited exceptional metabolic capabilities, effectively degrading a diverse range of substrates, including amino acids, organic acids, oils, n-alkanes, lignin, and aromatic monomers. Genomic analysis, coupled with biological experiments, revealed that strain A1-4-2 exhibited resistance to a very limited kind of antibiotics. Moreover, the strain’s biosafety, affirmed through zebrafish toxicity assays, underscores its suitability for environmental release. Additionally, the feasibility of genetic manipulation of strain A1-4-2 gives it the potential to become a chassis cell, enabling it to degrade organic pollutants more efficiently through genetic engineering. Our findings elucidate the strain’s genomic and metabolic attributes, offering insights into its biodegradation potentials and developing effective strategies for ecological restoration in face of pollution. |
| format | Article |
| id | doaj-art-c8e64879f54949e3ab3fbca8ed75104c |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-c8e64879f54949e3ab3fbca8ed75104c2025-08-20T03:45:23ZengNature PortfolioScientific Reports2045-23222025-07-0115111510.1038/s41598-025-05431-0A novel eco-friendly Acinetobacter strain A1-4-2 for bioremediation of aquatic pollutantsRui Wang0Jiahua Wang1Ling Wang2Yulun Cai3Yuan Wang4Huifang Luo5Bing Chen6Junlv Chen7Jiasong Fang8Zengfu Song9College of Fisheries and Life Science, Shanghai Ocean UniversityShanghai Engineering Center of Hadal Science and Technology, College of Oceanography and Ecological Science, Shanghai Ocean UniversityCollege of Fisheries and Life Science, Shanghai Ocean UniversityShanghai Engineering Center of Hadal Science and Technology, College of Oceanography and Ecological Science, Shanghai Ocean UniversityCollege of Fisheries and Life Science, Shanghai Ocean UniversityCollege of Fisheries and Life Science, Shanghai Ocean UniversityCollege of Fisheries and Life Science, Shanghai Ocean UniversityJiangsu Jingruite Environmental Protection Co., LtdShanghai Engineering Center of Hadal Science and Technology, College of Oceanography and Ecological Science, Shanghai Ocean UniversityCollege of Fisheries and Life Science, Shanghai Ocean UniversityAbstract The increasing accumulation of hydrocarbons and aromatic compounds in aquatic ecosystems, stemming from anthropogenic activities, poses severe ecological challenges, including disrupting biodiversity and threatening human health through the food chain. This study presents Acinetobacter strain A1-4-2, isolated from a hairy crab farming base, which could represent a novel Acinetobacter species. The metagenomic analysis of approximately 12,000 publicly available datasets revealed that this novel Acinetobacter species is widely distributed across various environments, particularly in those with high organic matter content, such as sludge, feces, and wastewater. Strain A1-4-2 exhibited exceptional metabolic capabilities, effectively degrading a diverse range of substrates, including amino acids, organic acids, oils, n-alkanes, lignin, and aromatic monomers. Genomic analysis, coupled with biological experiments, revealed that strain A1-4-2 exhibited resistance to a very limited kind of antibiotics. Moreover, the strain’s biosafety, affirmed through zebrafish toxicity assays, underscores its suitability for environmental release. Additionally, the feasibility of genetic manipulation of strain A1-4-2 gives it the potential to become a chassis cell, enabling it to degrade organic pollutants more efficiently through genetic engineering. Our findings elucidate the strain’s genomic and metabolic attributes, offering insights into its biodegradation potentials and developing effective strategies for ecological restoration in face of pollution.https://doi.org/10.1038/s41598-025-05431-0Novel AcinetobacterGenomicsMetabolismBioremediation |
| spellingShingle | Rui Wang Jiahua Wang Ling Wang Yulun Cai Yuan Wang Huifang Luo Bing Chen Junlv Chen Jiasong Fang Zengfu Song A novel eco-friendly Acinetobacter strain A1-4-2 for bioremediation of aquatic pollutants Scientific Reports Novel Acinetobacter Genomics Metabolism Bioremediation |
| title | A novel eco-friendly Acinetobacter strain A1-4-2 for bioremediation of aquatic pollutants |
| title_full | A novel eco-friendly Acinetobacter strain A1-4-2 for bioremediation of aquatic pollutants |
| title_fullStr | A novel eco-friendly Acinetobacter strain A1-4-2 for bioremediation of aquatic pollutants |
| title_full_unstemmed | A novel eco-friendly Acinetobacter strain A1-4-2 for bioremediation of aquatic pollutants |
| title_short | A novel eco-friendly Acinetobacter strain A1-4-2 for bioremediation of aquatic pollutants |
| title_sort | novel eco friendly acinetobacter strain a1 4 2 for bioremediation of aquatic pollutants |
| topic | Novel Acinetobacter Genomics Metabolism Bioremediation |
| url | https://doi.org/10.1038/s41598-025-05431-0 |
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