A systematic approach to pair secretory cargo receptors with their cargo suggests a mechanism for cargo selection by Erv14.

The endoplasmic reticulum (ER) is the site of synthesis of secreted and membrane proteins. To exit the ER, proteins are packaged into COPII vesicles through direct interaction with the COPII coat or aided by specific cargo receptors. Despite the fundamental role of such cargo receptors in protein tr...

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Bibliographic Details
Main Authors: Yonatan Herzig, Hayley J Sharpe, Yael Elbaz, Sean Munro, Maya Schuldiner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1001329&type=printable
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