Lyophilized human platelet lysate: manufacturing, quality control, and application

Lyophilized human platelet lysate: manufacturing, quality control, and application

BackgroundA significant number of platelet concentrates (PCs) is discarded daily in blood banks due to limited shelf life. Human platelet lysate (HPL), derived from expired PCs, has gained attention as an ethical and sustainable cell culture media supplement in biomedical research and cell therapy p...

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Main Authors:	Kerstin Wendland, Lea Koblin, Dirk Stobbe, Anna Dahms, Debora Singer, Sander Bekeschus, Jan Wesche, Janosch Schoon, Konstanze Aurich
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	human platelet lysate freeze drying lyophilization mesenchymal stromal cells sustainable cell culture HPL
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2025.1513444/full
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