Alternative cleavage and polyadenylation: key regulatory mechanisms in health and disease
Alternative polyadenylation (APA) is a critical post-transcriptional regulatory mechanism that generates diverse mRNA isoforms by selecting different polyadenylation sites within pre-mRNAs, thereby modulating the length of the 3’ untranslated region (3’ UTR), thereby fine-tuning gene expression and...
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| Main Authors: | Ying Zhang, Zikun Huang, Weiqing Lu, Zhaoyong Liu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
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| Series: | RNA Biology |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/15476286.2025.2529033 |
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