Evaluation of the Effectiveness of Vaccination of Russian Railways employees

Relevance. The effectiveness of vaccination of the working population against COVID-19 in the Russian background has not been studied enough.Aim. To evaluate the effectiveness of vaccination of the working population with Gam-COVID-Vak (Sputnik V) in the Russian Railways as an example.Materials &...

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Main Authors: N. A. Kostenko, E. A. Jidkova, A. A. Goriaev, I. V. Shangin, D. A. Khaltourina, Y. N. Matveyev, V. V. Ustyuzhanin, K. G. Gurevich
Format: Article
Language:Russian
Published: Numikom LLC 2022-11-01
Series:Эпидемиология и вакцинопрофилактика
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Online Access:https://www.epidemvac.ru/jour/article/view/1672
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author N. A. Kostenko
E. A. Jidkova
A. A. Goriaev
I. V. Shangin
D. A. Khaltourina
Y. N. Matveyev
V. V. Ustyuzhanin
K. G. Gurevich
author_facet N. A. Kostenko
E. A. Jidkova
A. A. Goriaev
I. V. Shangin
D. A. Khaltourina
Y. N. Matveyev
V. V. Ustyuzhanin
K. G. Gurevich
author_sort N. A. Kostenko
collection DOAJ
description Relevance. The effectiveness of vaccination of the working population against COVID-19 in the Russian background has not been studied enough.Aim. To evaluate the effectiveness of vaccination of the working population with Gam-COVID-Vak (Sputnik V) in the Russian Railways as an example.Materials & Methods.The effectiveness of vaccination with Sputnik V among employees of Russian Railways in the period from January 21 to November 31, 2021 was performed with the Cox regression method.Results. The effectiveness of Sputnik V against COVID-19 infection with was 97.8% (95% CI 97.8–97.9%) for two doses, 91.9% (95% CI 91.6–92.2%) for a single dose, and 97.9% (95% CI 97.6–98.1%) for revaccination, all after socio-demographic factors adjusted. The effectiveness of vaccination against COVID-19 with hospitalization was 97.5% for two doses of Sputnik V (95% CI 97.1–97.9%), 86.1% (95% CI 83.7–88.1%) for a single dose, and 98.2% (95% CI 96.3–99.2%) for revaccination. The effectiveness against lethal COVID-19 was 95.2% (95% CI 93.1–96.6%) for two doses of Sputnik V and 94.8% (95% CI 89–97.6%) for one dose. The high efficiency of vaccination could be associated with a fairly young age composition of the employees of the Russian Railways.Conclusions. The study showed the high effectiveness of vaccination with Sputnik V against COVID-19 among the working population.
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spelling doaj-art-c8d9cca2594d493394b87ebf3ccf9ea62025-08-20T03:57:18ZrusNumikom LLCЭпидемиология и вакцинопрофилактика2073-30462619-04942022-11-01215293710.31631/2073-3046-2022-21-5-29-37874Evaluation of the Effectiveness of Vaccination of Russian Railways employeesN. A. Kostenko0E. A. Jidkova1A. A. Goriaev2I. V. Shangin3D. A. Khaltourina4Y. N. Matveyev5V. V. Ustyuzhanin6K. G. Gurevich7JSC "Russian Railways"; Federal Research Budgetary Scientific Institution "Izmerov Research Institute of Occupational Health"JSC "Russian Railways"; The Moscow State University of Medicine and Dentistry;JSC "Russian Railways"JSC "Russian Railways"Federal Research Institute for Health Organization and Informatics of Ministry of Health of the Russian FederationMoscow Regional Research and Clinical InstituteNational Research University Higher School of EconomicsThe Moscow State University of Medicine and Dentistry; Research Institute of Health Organization and Medical Management of the Moscow City Health DepartmentRelevance. The effectiveness of vaccination of the working population against COVID-19 in the Russian background has not been studied enough.Aim. To evaluate the effectiveness of vaccination of the working population with Gam-COVID-Vak (Sputnik V) in the Russian Railways as an example.Materials & Methods.The effectiveness of vaccination with Sputnik V among employees of Russian Railways in the period from January 21 to November 31, 2021 was performed with the Cox regression method.Results. The effectiveness of Sputnik V against COVID-19 infection with was 97.8% (95% CI 97.8–97.9%) for two doses, 91.9% (95% CI 91.6–92.2%) for a single dose, and 97.9% (95% CI 97.6–98.1%) for revaccination, all after socio-demographic factors adjusted. The effectiveness of vaccination against COVID-19 with hospitalization was 97.5% for two doses of Sputnik V (95% CI 97.1–97.9%), 86.1% (95% CI 83.7–88.1%) for a single dose, and 98.2% (95% CI 96.3–99.2%) for revaccination. The effectiveness against lethal COVID-19 was 95.2% (95% CI 93.1–96.6%) for two doses of Sputnik V and 94.8% (95% CI 89–97.6%) for one dose. The high efficiency of vaccination could be associated with a fairly young age composition of the employees of the Russian Railways.Conclusions. The study showed the high effectiveness of vaccination with Sputnik V against COVID-19 among the working population.https://www.epidemvac.ru/jour/article/view/1672vaccinationcovid-19employeessputnik-vjsc «russian railways»observational study
spellingShingle N. A. Kostenko
E. A. Jidkova
A. A. Goriaev
I. V. Shangin
D. A. Khaltourina
Y. N. Matveyev
V. V. Ustyuzhanin
K. G. Gurevich
Evaluation of the Effectiveness of Vaccination of Russian Railways employees
Эпидемиология и вакцинопрофилактика
vaccination
covid-19
employees
sputnik-v
jsc «russian railways»
observational study
title Evaluation of the Effectiveness of Vaccination of Russian Railways employees
title_full Evaluation of the Effectiveness of Vaccination of Russian Railways employees
title_fullStr Evaluation of the Effectiveness of Vaccination of Russian Railways employees
title_full_unstemmed Evaluation of the Effectiveness of Vaccination of Russian Railways employees
title_short Evaluation of the Effectiveness of Vaccination of Russian Railways employees
title_sort evaluation of the effectiveness of vaccination of russian railways employees
topic vaccination
covid-19
employees
sputnik-v
jsc «russian railways»
observational study
url https://www.epidemvac.ru/jour/article/view/1672
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