Role of Nutrition in the Management of Hepatic Encephalopathy in End-Stage Liver Failure
Malnutrition is common in patients with end-stage liver failure and hepatic encephalopathy, and is considered a significant prognostic factor affecting quality of life, outcome, and survival. The liver plays a crucial role in the regulation of nutrition by trafficking the metabolism of nutrients, th...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Journal of Nutrition and Metabolism |
| Online Access: | http://dx.doi.org/10.1155/2010/489823 |
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| author | Chantal Bémeur Paul Desjardins Roger F. Butterworth |
| author_facet | Chantal Bémeur Paul Desjardins Roger F. Butterworth |
| author_sort | Chantal Bémeur |
| collection | DOAJ |
| description | Malnutrition is common in patients with end-stage liver failure and hepatic encephalopathy, and is considered a significant prognostic factor affecting quality of life, outcome, and survival. The liver plays a crucial role in the regulation of nutrition by trafficking the metabolism of nutrients, their distribution and appropriate use by the body. Nutritional consequences with the potential to cause nervous system dysfunction occur in liver failure, and many factors contribute to malnutrition in hepatic failure. Among them are inadequate dietary intake, malabsorption, increased protein losses, hypermetabolism, insulin resistance, gastrointestinal bleeding, ascites, inflammation/infection, and hyponatremia. Patients at risk of malnutrition are relatively difficult to identify since liver disease may interfere with biomarkers of malnutrition. The supplementation of the diet with amino acids, antioxidants, vitamins as well as probiotics in addition to meeting energy and protein requirements may improve nutritional status, liver function, and hepatic encephalopathy in patients with end-stage liver failure. |
| format | Article |
| id | doaj-art-c8d554c44f064e3bbeafc4597c25b488 |
| institution | Kabale University |
| issn | 2090-0724 2090-0732 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Nutrition and Metabolism |
| spelling | doaj-art-c8d554c44f064e3bbeafc4597c25b4882025-08-20T03:24:11ZengWileyJournal of Nutrition and Metabolism2090-07242090-07322010-01-01201010.1155/2010/489823489823Role of Nutrition in the Management of Hepatic Encephalopathy in End-Stage Liver FailureChantal Bémeur0Paul Desjardins1Roger F. Butterworth2Neuroscience Research Unit, CHUM, Saint-Luc Hospital, University of Montreal, 1058 St-Denis Street, Montreal, QC, CanadaNeuroscience Research Unit, CHUM, Saint-Luc Hospital, University of Montreal, 1058 St-Denis Street, Montreal, QC, CanadaNeuroscience Research Unit, CHUM, Saint-Luc Hospital, University of Montreal, 1058 St-Denis Street, Montreal, QC, CanadaMalnutrition is common in patients with end-stage liver failure and hepatic encephalopathy, and is considered a significant prognostic factor affecting quality of life, outcome, and survival. The liver plays a crucial role in the regulation of nutrition by trafficking the metabolism of nutrients, their distribution and appropriate use by the body. Nutritional consequences with the potential to cause nervous system dysfunction occur in liver failure, and many factors contribute to malnutrition in hepatic failure. Among them are inadequate dietary intake, malabsorption, increased protein losses, hypermetabolism, insulin resistance, gastrointestinal bleeding, ascites, inflammation/infection, and hyponatremia. Patients at risk of malnutrition are relatively difficult to identify since liver disease may interfere with biomarkers of malnutrition. The supplementation of the diet with amino acids, antioxidants, vitamins as well as probiotics in addition to meeting energy and protein requirements may improve nutritional status, liver function, and hepatic encephalopathy in patients with end-stage liver failure.http://dx.doi.org/10.1155/2010/489823 |
| spellingShingle | Chantal Bémeur Paul Desjardins Roger F. Butterworth Role of Nutrition in the Management of Hepatic Encephalopathy in End-Stage Liver Failure Journal of Nutrition and Metabolism |
| title | Role of Nutrition in the Management of Hepatic Encephalopathy in End-Stage Liver Failure |
| title_full | Role of Nutrition in the Management of Hepatic Encephalopathy in End-Stage Liver Failure |
| title_fullStr | Role of Nutrition in the Management of Hepatic Encephalopathy in End-Stage Liver Failure |
| title_full_unstemmed | Role of Nutrition in the Management of Hepatic Encephalopathy in End-Stage Liver Failure |
| title_short | Role of Nutrition in the Management of Hepatic Encephalopathy in End-Stage Liver Failure |
| title_sort | role of nutrition in the management of hepatic encephalopathy in end stage liver failure |
| url | http://dx.doi.org/10.1155/2010/489823 |
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