Mental Health Consequences of COVID‐19 Vaccine Side Effects: Findings From a Cross‐Sectional Analysis

ABSTRACT Background and Aims The COVID‐19 pandemic has intensified pre‐existing mental health issues in Bangladesh, yet no study has specifically examined how factors related to COVID‐19 vaccination influence mental health within this context. This study aimed to examine the relationship between men...

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Main Authors: Md. Shajadul Islam, Md. Bony Amin, Md. Hafizur Rahman, Fardana Binte Zaman, Sajib Rangder, Faiaz Morshed Khan Jilan, Wajihantun Nesa Chowdhury, Sanjarah Tamim, Nusrat Jahan Hridi, Md. Hasanuzzaman, Md. Shafiqul Islam Khan
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Health Science Reports
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Online Access:https://doi.org/10.1002/hsr2.70998
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author Md. Shajadul Islam
Md. Bony Amin
Md. Hafizur Rahman
Fardana Binte Zaman
Sajib Rangder
Faiaz Morshed Khan Jilan
Wajihantun Nesa Chowdhury
Sanjarah Tamim
Nusrat Jahan Hridi
Md. Hasanuzzaman
Md. Shafiqul Islam Khan
author_facet Md. Shajadul Islam
Md. Bony Amin
Md. Hafizur Rahman
Fardana Binte Zaman
Sajib Rangder
Faiaz Morshed Khan Jilan
Wajihantun Nesa Chowdhury
Sanjarah Tamim
Nusrat Jahan Hridi
Md. Hasanuzzaman
Md. Shafiqul Islam Khan
author_sort Md. Shajadul Islam
collection DOAJ
description ABSTRACT Background and Aims The COVID‐19 pandemic has intensified pre‐existing mental health issues in Bangladesh, yet no study has specifically examined how factors related to COVID‐19 vaccination influence mental health within this context. This study aimed to examine the relationship between mental health symptoms, including depression, anxiety, and stress, and COVID‐19 vaccination status and related factors among the adult Bangladeshi population. Methods A cross‐sectional study with a convenience sampling technique was employed to gather the data. The sample size and response rate were 1085 and 93.68%. The mean age of the participants was 34.30 (SD: 12.79), and 55.3% were female. Descriptive and inferential statistics were carried out. Results The reliability of the instruments, measured by Cronbach's alpha, was: depression (0.78), anxiety (0.82), stress (0.83), and overall DASS (0.92). The average number of COVID‐19 vaccine doses taken was 2.33. Each additional dose of the COVID‐19 vaccine significantly reduces stress scores by 0.61. Additionally, pre‐vaccination concerns about side effects significantly increase anxiety scores by 0.63. Furthermore, experiencing pressure to get vaccinated is associated with a significant increase in depression scores by 0.78. Moreover, experiencing negative outcomes from the vaccine significantly decreases scores across all three mental health metrics: depression by −0.91, anxiety by −0.87, and stress by −1.35. Conclusion This study reveals the broad psychological consequences of COVID‐19 vaccination in Bangladesh, which underscore the importance of effective communication and supportive strategies, alongside targeted psychological interventions at vaccination sites.
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spelling doaj-art-c8d54c8b25114308b01d1a056c4fe7082025-08-20T04:02:00ZengWileyHealth Science Reports2398-88352025-07-0187n/an/a10.1002/hsr2.70998Mental Health Consequences of COVID‐19 Vaccine Side Effects: Findings From a Cross‐Sectional AnalysisMd. Shajadul Islam0Md. Bony Amin1Md. Hafizur Rahman2Fardana Binte Zaman3Sajib Rangder4Faiaz Morshed Khan Jilan5Wajihantun Nesa Chowdhury6Sanjarah Tamim7Nusrat Jahan Hridi8Md. Hasanuzzaman9Md. Shafiqul Islam Khan10Department of Food Microbiology, Faculty of Nutrition and Food Science Patuakhali Science and Technology University Patuakhali BangladeshDepartment of Environmental Health and Sanitation, Faculty of Nutrition and Food Science Patuakhali Science and Technology University Patuakhali BangladeshDepartment of Environmental Health and Sanitation, Faculty of Nutrition and Food Science Patuakhali Science and Technology University Patuakhali BangladeshInterdisciplinary Institute for Food Security Bangladesh Agricultural University Mymensingh BangladeshFaculty of Nutrition and Food Science Patuakhali Science and Technology University Patuakhali BangladeshFaculty of Nutrition and Food Science Patuakhali Science and Technology University Patuakhali BangladeshFaculty of Nutrition and Food Science Patuakhali Science and Technology University Patuakhali BangladeshFaculty of Nutrition and Food Science Patuakhali Science and Technology University Patuakhali BangladeshFaculty of Nutrition and Food Science Patuakhali Science and Technology University Patuakhali BangladeshDepartment of Environmental Health and Sanitation, Faculty of Nutrition and Food Science Patuakhali Science and Technology University Patuakhali BangladeshDepartment of Cellular and Molecular Biology, Faculty of Biotechnology and Genetic Engineering Chattogram Veterinary and Animal Sciences University Chattogram BangladeshABSTRACT Background and Aims The COVID‐19 pandemic has intensified pre‐existing mental health issues in Bangladesh, yet no study has specifically examined how factors related to COVID‐19 vaccination influence mental health within this context. This study aimed to examine the relationship between mental health symptoms, including depression, anxiety, and stress, and COVID‐19 vaccination status and related factors among the adult Bangladeshi population. Methods A cross‐sectional study with a convenience sampling technique was employed to gather the data. The sample size and response rate were 1085 and 93.68%. The mean age of the participants was 34.30 (SD: 12.79), and 55.3% were female. Descriptive and inferential statistics were carried out. Results The reliability of the instruments, measured by Cronbach's alpha, was: depression (0.78), anxiety (0.82), stress (0.83), and overall DASS (0.92). The average number of COVID‐19 vaccine doses taken was 2.33. Each additional dose of the COVID‐19 vaccine significantly reduces stress scores by 0.61. Additionally, pre‐vaccination concerns about side effects significantly increase anxiety scores by 0.63. Furthermore, experiencing pressure to get vaccinated is associated with a significant increase in depression scores by 0.78. Moreover, experiencing negative outcomes from the vaccine significantly decreases scores across all three mental health metrics: depression by −0.91, anxiety by −0.87, and stress by −1.35. Conclusion This study reveals the broad psychological consequences of COVID‐19 vaccination in Bangladesh, which underscore the importance of effective communication and supportive strategies, alongside targeted psychological interventions at vaccination sites.https://doi.org/10.1002/hsr2.70998mental healthside effectsvaccine adverse effectsvaccines
spellingShingle Md. Shajadul Islam
Md. Bony Amin
Md. Hafizur Rahman
Fardana Binte Zaman
Sajib Rangder
Faiaz Morshed Khan Jilan
Wajihantun Nesa Chowdhury
Sanjarah Tamim
Nusrat Jahan Hridi
Md. Hasanuzzaman
Md. Shafiqul Islam Khan
Mental Health Consequences of COVID‐19 Vaccine Side Effects: Findings From a Cross‐Sectional Analysis
Health Science Reports
mental health
side effects
vaccine adverse effects
vaccines
title Mental Health Consequences of COVID‐19 Vaccine Side Effects: Findings From a Cross‐Sectional Analysis
title_full Mental Health Consequences of COVID‐19 Vaccine Side Effects: Findings From a Cross‐Sectional Analysis
title_fullStr Mental Health Consequences of COVID‐19 Vaccine Side Effects: Findings From a Cross‐Sectional Analysis
title_full_unstemmed Mental Health Consequences of COVID‐19 Vaccine Side Effects: Findings From a Cross‐Sectional Analysis
title_short Mental Health Consequences of COVID‐19 Vaccine Side Effects: Findings From a Cross‐Sectional Analysis
title_sort mental health consequences of covid 19 vaccine side effects findings from a cross sectional analysis
topic mental health
side effects
vaccine adverse effects
vaccines
url https://doi.org/10.1002/hsr2.70998
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