Increased Zinc Serum Level: New Clues in Babol Stroke Patients, Northern Iran
Background. Stroke is the second leading cause of death worldwide. The role of zinc as a new predictor of stroke was considered. Methods. This prospective study was conducted in Ayatollah Rouhani Hospital within a year on 100 stroke and 100 control patients. Findings. The difference in zinc serum le...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Stroke Research and Treatment |
| Online Access: | http://dx.doi.org/10.1155/2018/7681682 |
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| author | Alijan Ahmadi Ahangar Payam Saadat Sona Niroomand Shayan Alijanpour Reza Sohrabnezhad Alireza Firozejahi Mohamad Ali Biani Fatemeh Arab Hamed Hosseinzadeh Sekine Faraji Jalal Niroomand |
| author_facet | Alijan Ahmadi Ahangar Payam Saadat Sona Niroomand Shayan Alijanpour Reza Sohrabnezhad Alireza Firozejahi Mohamad Ali Biani Fatemeh Arab Hamed Hosseinzadeh Sekine Faraji Jalal Niroomand |
| author_sort | Alijan Ahmadi Ahangar |
| collection | DOAJ |
| description | Background. Stroke is the second leading cause of death worldwide. The role of zinc as a new predictor of stroke was considered. Methods. This prospective study was conducted in Ayatollah Rouhani Hospital within a year on 100 stroke and 100 control patients. Findings. The difference in zinc serum level in two groups was significant (deficiency: 3 (3%) in patients versus 20 (20%) in control group, normal: 25 (25%) versus 54 (54%), and increased level: 72 (72%) versus 26 (26%); p<0.001). Difference in zinc serum levels was statistically significant with ischemic heart disease (deficiency: 0 cases (0%), normal: 8 cases (24%), increased level: 24 cases (75%), p=0.003). Increases in zinc serum level were significantly correlated with the frequency of hemorrhagic and ischemic patients (deficiency: 3 (3.3%) hemorrhagic versus 0 (0%) ischemic; normal: 19 (21%) versus 6 (60%), increased level: 68 (75.6%) versus 4 (40%); p=0.025). Regression logistics showed that ischemic heart disease (p<0.001; OR = 28.29, %95 CI: 5.53; 144.87), hyperlipidemia (p<0.001; OR = 0.26, %95 CI: 0.12; 0.56), and zinc serum level (p<0.001, OR = 15.53, %95 CI: 4.03; 59.83) each had a significant role. Conclusions. Babol stroke patients are prone to increased zinc serum level as a new parameter. Ischemic heart disease, increased levels of zinc, and hyperlipidemia were found to be probable predictor factors for stroke in Babol. |
| format | Article |
| id | doaj-art-c8d467d2a5e349a9be62a0e888a8c17f |
| institution | OA Journals |
| issn | 2090-8105 2042-0056 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stroke Research and Treatment |
| spelling | doaj-art-c8d467d2a5e349a9be62a0e888a8c17f2025-08-20T02:19:41ZengWileyStroke Research and Treatment2090-81052042-00562018-01-01201810.1155/2018/76816827681682Increased Zinc Serum Level: New Clues in Babol Stroke Patients, Northern IranAlijan Ahmadi Ahangar0Payam Saadat1Sona Niroomand2Shayan Alijanpour3Reza Sohrabnezhad4Alireza Firozejahi5Mohamad Ali Biani6Fatemeh Arab7Hamed Hosseinzadeh8Sekine Faraji9Jalal Niroomand10Mobility Impairment Research Center, Babol University of Medical Sciences, Babol, IranMobility Impairment Research Center, Babol University of Medical Sciences, Babol, IranDepartment of Chemistry, Payame Noor University, Tehran, IranStudent Research Committee, Isfahan University of Medical Science, Isfahan, IranAyatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, IranAyatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, IranAyatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, IranBabol University of Medical Sciences, Babol, IranAyatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, IranAyatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, IranBabol University of Medical Sciences, Babol, IranBackground. Stroke is the second leading cause of death worldwide. The role of zinc as a new predictor of stroke was considered. Methods. This prospective study was conducted in Ayatollah Rouhani Hospital within a year on 100 stroke and 100 control patients. Findings. The difference in zinc serum level in two groups was significant (deficiency: 3 (3%) in patients versus 20 (20%) in control group, normal: 25 (25%) versus 54 (54%), and increased level: 72 (72%) versus 26 (26%); p<0.001). Difference in zinc serum levels was statistically significant with ischemic heart disease (deficiency: 0 cases (0%), normal: 8 cases (24%), increased level: 24 cases (75%), p=0.003). Increases in zinc serum level were significantly correlated with the frequency of hemorrhagic and ischemic patients (deficiency: 3 (3.3%) hemorrhagic versus 0 (0%) ischemic; normal: 19 (21%) versus 6 (60%), increased level: 68 (75.6%) versus 4 (40%); p=0.025). Regression logistics showed that ischemic heart disease (p<0.001; OR = 28.29, %95 CI: 5.53; 144.87), hyperlipidemia (p<0.001; OR = 0.26, %95 CI: 0.12; 0.56), and zinc serum level (p<0.001, OR = 15.53, %95 CI: 4.03; 59.83) each had a significant role. Conclusions. Babol stroke patients are prone to increased zinc serum level as a new parameter. Ischemic heart disease, increased levels of zinc, and hyperlipidemia were found to be probable predictor factors for stroke in Babol.http://dx.doi.org/10.1155/2018/7681682 |
| spellingShingle | Alijan Ahmadi Ahangar Payam Saadat Sona Niroomand Shayan Alijanpour Reza Sohrabnezhad Alireza Firozejahi Mohamad Ali Biani Fatemeh Arab Hamed Hosseinzadeh Sekine Faraji Jalal Niroomand Increased Zinc Serum Level: New Clues in Babol Stroke Patients, Northern Iran Stroke Research and Treatment |
| title | Increased Zinc Serum Level: New Clues in Babol Stroke Patients, Northern Iran |
| title_full | Increased Zinc Serum Level: New Clues in Babol Stroke Patients, Northern Iran |
| title_fullStr | Increased Zinc Serum Level: New Clues in Babol Stroke Patients, Northern Iran |
| title_full_unstemmed | Increased Zinc Serum Level: New Clues in Babol Stroke Patients, Northern Iran |
| title_short | Increased Zinc Serum Level: New Clues in Babol Stroke Patients, Northern Iran |
| title_sort | increased zinc serum level new clues in babol stroke patients northern iran |
| url | http://dx.doi.org/10.1155/2018/7681682 |
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