Nasal Injuries Related to Respiratory Support Interfaces in Preterm Infants: Neonatal Course and 12-Month Outcome
<i>Background</i>: Respiratory support required by preterm infants involves contact between their immature skin and ventilation devices, which can lead to skin breakdown. <i>Methods</i>: A prospective observational study including newborns with a nasal injury related to respi...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-06-01
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| Series: | Children |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-9067/12/7/840 |
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| Summary: | <i>Background</i>: Respiratory support required by preterm infants involves contact between their immature skin and ventilation devices, which can lead to skin breakdown. <i>Methods</i>: A prospective observational study including newborns with a nasal injury related to respiratory support, born at gestational age < 33 weeks, from May 2020 to January 2022, in the neonatal intensive care unit of Strasbourg. Injuries were recorded using a validated scale at inclusion and 3, 7 and 28 days. Sequelae were evaluated at discharge and 4, 9 and 12 months post-menstrual age. <i>Results</i>: In total, 64/276 newborns (23%) had a nasal injury. Most of the injuries were stage 2 (34/64, 53%) and stage 1 (25/64, 39%). The interface most frequently associated with injury was continuous positive airway pressure (53/64, 83%). Favorable evolution was associated with the injury site (<i>p</i> < 0.01) and the type of respiratory support needed when collecting at the 28th day (<i>p</i> = 0.04). At discharge, 34/58 infants (59%) had sequelae. The presence of a scar was associated with the maximum injury severity (<i>p</i> < 0.001) and total duration of respiratory support (<i>p</i> = 0.02). At 12 months, 31/47 infants (66%) had esthetic sequelae. <i>Conclusions</i>: Nasal injuries related to respiratory support in preterm infants were frequent, and more than half of the injuries resulted in medium-term sequelae. |
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| ISSN: | 2227-9067 |