The Osteoarthritis Thumb Therapy (OTTER) II Trial: a study protocol for a three-arm multi-centre randomised placebo controlled trial of the clinical effectiveness and efficacy and cost-effectiveness of splints for symptomatic thumb base osteoarthritis

The Osteoarthritis Thumb Therapy (OTTER) II Trial: a study protocol for a three-arm multi-centre randomised placebo controlled trial of the clinical effectiveness and efficacy and cost-effectiveness of splints for symptomatic thumb base osteoarthritis

Introduction The economic cost of osteoarthritis (OA) is high. At least 4.4 million people have hand OA in the UK. Symptomatic thumb base OA affects 20% of people over 55 years, causing more pain, work and functional disability than OA elsewhere in the hand. Most evidence-based guidelines recommend...

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Main Authors: Michael Doherty, Rachael Gooberman-Hill, Susan Dutton, Peter White, Nigel K Arden, Mark Williams, Jo Adams, Paula Barratt, Sofia Barbosa Bouças, Sarah Bradley, Krysia Dziedzic, Kelly Hislop Lennie, Corinne Hutt Greenyer, Victoria Jansen, Ramon Luengo-Fernandez, Claire Meagher
Format: Article
Language:English
Published: BMJ Publishing Group 2019-10-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/9/10/e028342.full
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