Two-Dimensional Simulation on the Critical Diameter of Particles in Asymmetric I-Shaped DLD Arrays
Deterministic lateral displacement (DLD) is a passive particle separation method based on microfluidic technology, with its separation mechanism primarily relying on particle size differences. Therefore, the critical separation size is of great significance in the design of DLD devices. The geometri...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-02-01
|
| Series: | Micromachines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-666X/16/3/270 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850091052522799104 |
|---|---|
| author | Jiangbo Wu Zihan Yan Yongqing He Jie Liu Yao Lv |
| author_facet | Jiangbo Wu Zihan Yan Yongqing He Jie Liu Yao Lv |
| author_sort | Jiangbo Wu |
| collection | DOAJ |
| description | Deterministic lateral displacement (DLD) is a passive particle separation method based on microfluidic technology, with its separation mechanism primarily relying on particle size differences. Therefore, the critical separation size is of great significance in the design of DLD devices. The geometric asymmetry of the pillar array design significantly influences fluid behavior and critical particle size variations. This study first analyzed particle motion characteristics through particle trajectory observation experiments within asymmetric microfluidic chips. Subsequently, a two-dimensional numerical simulation method was employed to investigate the effects of three different ratios of lateral gap size to downstream gap size (G<sub>x</sub>:G<sub>y</sub>) on particle trajectories and flow field distribution. The results indicate that as G<sub>x</sub>:G<sub>y</sub> decreases, the upward flow rate gradually reduces, accompanied by changes in the flow field velocity distribution, causing particles to favor displacement mode. This study provides new theoretical foundations for the precise regulation of particle motion behavior and introduces novel insights for optimizing DLD device design. |
| format | Article |
| id | doaj-art-c8d103854dc4425489f9cfc3e9dcf724 |
| institution | DOAJ |
| issn | 2072-666X |
| language | English |
| publishDate | 2025-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Micromachines |
| spelling | doaj-art-c8d103854dc4425489f9cfc3e9dcf7242025-08-20T02:42:27ZengMDPI AGMicromachines2072-666X2025-02-0116327010.3390/mi16030270Two-Dimensional Simulation on the Critical Diameter of Particles in Asymmetric I-Shaped DLD ArraysJiangbo Wu0Zihan Yan1Yongqing He2Jie Liu3Yao Lv4School of Energy and Power Engineering, Lanzhou University of Technology, Lanzhou 730050, ChinaSchool of Energy and Power Engineering, Lanzhou University of Technology, Lanzhou 730050, ChinaChongqing Key Laboratory of Micro-Nano System and Intelligent Sensing, Chongqing Technology and Business University, Chongqing 400067, ChinaSchool of Energy and Power Engineering, Lanzhou University of Technology, Lanzhou 730050, ChinaSchool of Energy and Power Engineering, Lanzhou University of Technology, Lanzhou 730050, ChinaDeterministic lateral displacement (DLD) is a passive particle separation method based on microfluidic technology, with its separation mechanism primarily relying on particle size differences. Therefore, the critical separation size is of great significance in the design of DLD devices. The geometric asymmetry of the pillar array design significantly influences fluid behavior and critical particle size variations. This study first analyzed particle motion characteristics through particle trajectory observation experiments within asymmetric microfluidic chips. Subsequently, a two-dimensional numerical simulation method was employed to investigate the effects of three different ratios of lateral gap size to downstream gap size (G<sub>x</sub>:G<sub>y</sub>) on particle trajectories and flow field distribution. The results indicate that as G<sub>x</sub>:G<sub>y</sub> decreases, the upward flow rate gradually reduces, accompanied by changes in the flow field velocity distribution, causing particles to favor displacement mode. This study provides new theoretical foundations for the precise regulation of particle motion behavior and introduces novel insights for optimizing DLD device design.https://www.mdpi.com/2072-666X/16/3/270deterministic lateral displacementfinite element methodcritical separation sizemicro fluids |
| spellingShingle | Jiangbo Wu Zihan Yan Yongqing He Jie Liu Yao Lv Two-Dimensional Simulation on the Critical Diameter of Particles in Asymmetric I-Shaped DLD Arrays Micromachines deterministic lateral displacement finite element method critical separation size micro fluids |
| title | Two-Dimensional Simulation on the Critical Diameter of Particles in Asymmetric I-Shaped DLD Arrays |
| title_full | Two-Dimensional Simulation on the Critical Diameter of Particles in Asymmetric I-Shaped DLD Arrays |
| title_fullStr | Two-Dimensional Simulation on the Critical Diameter of Particles in Asymmetric I-Shaped DLD Arrays |
| title_full_unstemmed | Two-Dimensional Simulation on the Critical Diameter of Particles in Asymmetric I-Shaped DLD Arrays |
| title_short | Two-Dimensional Simulation on the Critical Diameter of Particles in Asymmetric I-Shaped DLD Arrays |
| title_sort | two dimensional simulation on the critical diameter of particles in asymmetric i shaped dld arrays |
| topic | deterministic lateral displacement finite element method critical separation size micro fluids |
| url | https://www.mdpi.com/2072-666X/16/3/270 |
| work_keys_str_mv | AT jiangbowu twodimensionalsimulationonthecriticaldiameterofparticlesinasymmetricishapeddldarrays AT zihanyan twodimensionalsimulationonthecriticaldiameterofparticlesinasymmetricishapeddldarrays AT yongqinghe twodimensionalsimulationonthecriticaldiameterofparticlesinasymmetricishapeddldarrays AT jieliu twodimensionalsimulationonthecriticaldiameterofparticlesinasymmetricishapeddldarrays AT yaolv twodimensionalsimulationonthecriticaldiameterofparticlesinasymmetricishapeddldarrays |