High rates of same-sex attraction/gender nonconformity in the offspring of mothers with thyroid dysfunction during pregnancy: proposal of prenatal thyroid model

Both youngsters and adults with same-sex attraction are at greater risk for negative health outcomes. Despite mounting efforts to determine the biological background, a satisfactory conclusion has not been reached and there is a need to explore alternate factors like functioning of thyroid system du...

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Main Author: Osman Sabuncuoglu
Format: Article
Language:English
Published: Wiley 2015-09-01
Series:Mental Illness
Subjects:
Online Access:http://www.pagepress.org/journals/index.php/mi/article/view/5810
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author Osman Sabuncuoglu
author_facet Osman Sabuncuoglu
author_sort Osman Sabuncuoglu
collection DOAJ
description Both youngsters and adults with same-sex attraction are at greater risk for negative health outcomes. Despite mounting efforts to determine the biological background, a satisfactory conclusion has not been reached and there is a need to explore alternate factors like functioning of thyroid system during pregnancy. A retrospective chart review was undertaken of 790 eligible children and adolescents who had been admitted to child psychiatry between 2005 and 2013. This population consisted of 520 (65%) males and 270 (35%) females, aged 8 to 17 years. Fifteen mothers (1.8%) were found to have a history of thyroid dysfunction during pregnancy. Sixteen youngsters (2%) had a history of same-sex attraction. Twelve overlapping cases with both same-sex attraction and maternal thyroid dysfunction during pregnancy were identified, which was extremely significant (P<0.0001, by Fisher’s exact test). The association was also significant for each sex (P<0.0001, by Fisher’s exact test). There is evidence that thyroid gland plays a crucial and decisive role in determining sexual orientation in people. Maternal thyroid dysfunctions during pregnancy may result in homosexual orientation in the offspring.
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spelling doaj-art-c8c3e1ee4a4e4d49ad6695e5a3970b5a2025-08-20T03:05:10ZengWileyMental Illness2036-74572036-74652015-09-017210.4081/mi.2015.58103203High rates of same-sex attraction/gender nonconformity in the offspring of mothers with thyroid dysfunction during pregnancy: proposal of prenatal thyroid modelOsman Sabuncuoglu0Department of Child and Adolescent Psychiatry, School of Medicine, Marmara University Hospital, IstanbulBoth youngsters and adults with same-sex attraction are at greater risk for negative health outcomes. Despite mounting efforts to determine the biological background, a satisfactory conclusion has not been reached and there is a need to explore alternate factors like functioning of thyroid system during pregnancy. A retrospective chart review was undertaken of 790 eligible children and adolescents who had been admitted to child psychiatry between 2005 and 2013. This population consisted of 520 (65%) males and 270 (35%) females, aged 8 to 17 years. Fifteen mothers (1.8%) were found to have a history of thyroid dysfunction during pregnancy. Sixteen youngsters (2%) had a history of same-sex attraction. Twelve overlapping cases with both same-sex attraction and maternal thyroid dysfunction during pregnancy were identified, which was extremely significant (P<0.0001, by Fisher’s exact test). The association was also significant for each sex (P<0.0001, by Fisher’s exact test). There is evidence that thyroid gland plays a crucial and decisive role in determining sexual orientation in people. Maternal thyroid dysfunctions during pregnancy may result in homosexual orientation in the offspring.http://www.pagepress.org/journals/index.php/mi/article/view/5810Sexual orientationhomosexualitythyroid diseasesprenatal exposure delayed effectadolescents
spellingShingle Osman Sabuncuoglu
High rates of same-sex attraction/gender nonconformity in the offspring of mothers with thyroid dysfunction during pregnancy: proposal of prenatal thyroid model
Mental Illness
Sexual orientation
homosexuality
thyroid diseases
prenatal exposure delayed effect
adolescents
title High rates of same-sex attraction/gender nonconformity in the offspring of mothers with thyroid dysfunction during pregnancy: proposal of prenatal thyroid model
title_full High rates of same-sex attraction/gender nonconformity in the offspring of mothers with thyroid dysfunction during pregnancy: proposal of prenatal thyroid model
title_fullStr High rates of same-sex attraction/gender nonconformity in the offspring of mothers with thyroid dysfunction during pregnancy: proposal of prenatal thyroid model
title_full_unstemmed High rates of same-sex attraction/gender nonconformity in the offspring of mothers with thyroid dysfunction during pregnancy: proposal of prenatal thyroid model
title_short High rates of same-sex attraction/gender nonconformity in the offspring of mothers with thyroid dysfunction during pregnancy: proposal of prenatal thyroid model
title_sort high rates of same sex attraction gender nonconformity in the offspring of mothers with thyroid dysfunction during pregnancy proposal of prenatal thyroid model
topic Sexual orientation
homosexuality
thyroid diseases
prenatal exposure delayed effect
adolescents
url http://www.pagepress.org/journals/index.php/mi/article/view/5810
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