Bioactivity of Combination Elephantopus scaber and Sauropus androgynus on the Level of B220 cells of Lymph Node in Pregnant Typhoid BALB/c Mice

Elephantopus scaber and Sauropus androgynus are herbal remedies that contain flavonoids as immunomodulatory agents. This study was aimed to observe the changes in the relative number of B cells in lymph node tissue of pregnant typhoid mice. Mice were divided into seven groups K-, K+, E. scaber 200 m...

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Main Authors: Lulut Dwi Nurmamulyosari, Muhammad Sasmito Djati, Sri Widyarti
Format: Article
Language:English
Published: University of Brawijaya 2015-12-01
Series:Journal of Experimental Life Science
Subjects:
Online Access:https://jels.ub.ac.id/index.php/jels/article/view/151
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author Lulut Dwi Nurmamulyosari
Muhammad Sasmito Djati
Sri Widyarti
author_facet Lulut Dwi Nurmamulyosari
Muhammad Sasmito Djati
Sri Widyarti
author_sort Lulut Dwi Nurmamulyosari
collection DOAJ
description Elephantopus scaber and Sauropus androgynus are herbal remedies that contain flavonoids as immunomodulatory agents. This study was aimed to observe the changes in the relative number of B cells in lymph node tissue of pregnant typhoid mice. Mice were divided into seven groups K-, K+, E. scaber 200 mg.kg-1 BW, E. scaber 150 mg.kg-1 BW + S. androgynus 37.5 mg.kg-1 BW, E. scaber 100 mg.kg-1 BW + S. androgynus 75 mg.kg-1 BW, E. scaber 50 mg.kg-1 BW + S. androgynus 112.5 mg.kg-1 BW, dan S. androgynus 150 mg.kg-1 BW. Mice were dissected on the 12th and 18th day after herbal treatment. Data was analyzed using one way ANOVA (p < 0.05) and Duncan. The result show that E. scaber combination of 200 mg.kg-1 BW and E. scaber 150 mg.kg-1 BW + S. androgynus 37.5 mg.kg-1 BW can increase the number of B220 cells (p < 0,05) on pregnant mice typoid model.
format Article
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issn 2087-2852
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publishDate 2015-12-01
publisher University of Brawijaya
record_format Article
series Journal of Experimental Life Science
spelling doaj-art-c8c1981ce46245c3881d47525f07d3102025-08-20T03:13:10ZengUniversity of BrawijayaJournal of Experimental Life Science2087-28522338-16552015-12-01526871https://doi.org/10.21776/ub.jels.2015.005.02.03Bioactivity of Combination Elephantopus scaber and Sauropus androgynus on the Level of B220 cells of Lymph Node in Pregnant Typhoid BALB/c MiceLulut Dwi Nurmamulyosari0Muhammad Sasmito Djati1Sri Widyarti2Universitas Brawijaya, Malang, IndonesiaUniversitas Brawijaya, Malang, IndonesiaUniversitas Brawijaya, Malang, IndonesiaElephantopus scaber and Sauropus androgynus are herbal remedies that contain flavonoids as immunomodulatory agents. This study was aimed to observe the changes in the relative number of B cells in lymph node tissue of pregnant typhoid mice. Mice were divided into seven groups K-, K+, E. scaber 200 mg.kg-1 BW, E. scaber 150 mg.kg-1 BW + S. androgynus 37.5 mg.kg-1 BW, E. scaber 100 mg.kg-1 BW + S. androgynus 75 mg.kg-1 BW, E. scaber 50 mg.kg-1 BW + S. androgynus 112.5 mg.kg-1 BW, dan S. androgynus 150 mg.kg-1 BW. Mice were dissected on the 12th and 18th day after herbal treatment. Data was analyzed using one way ANOVA (p < 0.05) and Duncan. The result show that E. scaber combination of 200 mg.kg-1 BW and E. scaber 150 mg.kg-1 BW + S. androgynus 37.5 mg.kg-1 BW can increase the number of B220 cells (p < 0,05) on pregnant mice typoid model.https://jels.ub.ac.id/index.php/jels/article/view/151b220elephantopus scaberpregnantsauropus androgynustyphoid fever
spellingShingle Lulut Dwi Nurmamulyosari
Muhammad Sasmito Djati
Sri Widyarti
Bioactivity of Combination Elephantopus scaber and Sauropus androgynus on the Level of B220 cells of Lymph Node in Pregnant Typhoid BALB/c Mice
Journal of Experimental Life Science
b220
elephantopus scaber
pregnant
sauropus androgynus
typhoid fever
title Bioactivity of Combination Elephantopus scaber and Sauropus androgynus on the Level of B220 cells of Lymph Node in Pregnant Typhoid BALB/c Mice
title_full Bioactivity of Combination Elephantopus scaber and Sauropus androgynus on the Level of B220 cells of Lymph Node in Pregnant Typhoid BALB/c Mice
title_fullStr Bioactivity of Combination Elephantopus scaber and Sauropus androgynus on the Level of B220 cells of Lymph Node in Pregnant Typhoid BALB/c Mice
title_full_unstemmed Bioactivity of Combination Elephantopus scaber and Sauropus androgynus on the Level of B220 cells of Lymph Node in Pregnant Typhoid BALB/c Mice
title_short Bioactivity of Combination Elephantopus scaber and Sauropus androgynus on the Level of B220 cells of Lymph Node in Pregnant Typhoid BALB/c Mice
title_sort bioactivity of combination elephantopus scaber and sauropus androgynus on the level of b220 cells of lymph node in pregnant typhoid balb c mice
topic b220
elephantopus scaber
pregnant
sauropus androgynus
typhoid fever
url https://jels.ub.ac.id/index.php/jels/article/view/151
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