Influencing factors and dynamic changes of COVID-19 vaccine hesitancy in China: From the perspective of machine learning analysis

Exploring the influencing factors of COVID-19 vaccine hesitancy and summarizing countermeasures is of great significance for effectively addressing potential public health crises. Based on survey data from China, we employed a Gradient Boosting Decision Tree (GBDT) model and conducted SHAP interpret...

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Main Authors: Lei Li, Hui Jing, Yuqi Zhao, Shenghua Wu, Boyu Zhu
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/21645515.2025.2536898
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author Lei Li
Hui Jing
Yuqi Zhao
Shenghua Wu
Boyu Zhu
author_facet Lei Li
Hui Jing
Yuqi Zhao
Shenghua Wu
Boyu Zhu
author_sort Lei Li
collection DOAJ
description Exploring the influencing factors of COVID-19 vaccine hesitancy and summarizing countermeasures is of great significance for effectively addressing potential public health crises. Based on survey data from China, we employed a Gradient Boosting Decision Tree (GBDT) model and conducted SHAP interpretability analysis. The results show that in the primary series of COVID−19 vaccines, the important factors include social norms, vaccine knowledge, anticipated regret, age, vaccine safety, social responsibility, education level, religious belief, vaccine effectiveness, and perceived severity. While for booster shots, the important variables include age, vaccination experience, vaccine knowledge, vaccine effectiveness, gender, perceived severity, concerns about the epidemic, social norms, anticipated regret, and sense of social responsibility. The differences in the composition and significance of these core predictive factors suggest that COVID-19 vaccine hesitancy is dynamically evolving. This pattern of evolution is manifested as a shift in the decision – making basis from social norms to subjective experiences, in the focus of vaccines from safety – first to effectiveness – priority, and in the decision – making mechanism from emotion – dominated to cognition – driven. The research findings inspire us that when formulating vaccination strategies, multiple factors need to be comprehensively considered. Moreover, strategies should be adjusted in a timely manner according to changes in the vaccination stages to align with the shift in public concerns and decision – making mechanisms.
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spelling doaj-art-c8bddc0400f84d8db256498d5510f1b22025-08-20T03:31:54ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2025-12-0121110.1080/21645515.2025.2536898Influencing factors and dynamic changes of COVID-19 vaccine hesitancy in China: From the perspective of machine learning analysisLei Li0Hui Jing1Yuqi Zhao2Shenghua Wu3Boyu Zhu4School of Law, Huaibei Normal University, Huaibei, ChinaSchool of Computer Science and Technology, Huaibei Normal University, Huaibei, ChinaCollege of Law, University of Birmingham, Birmingham, UKSchool of Law, Huaibei Normal University, Huaibei, ChinaSchool of Sociology, Wuhan University, Wuhan, ChinaExploring the influencing factors of COVID-19 vaccine hesitancy and summarizing countermeasures is of great significance for effectively addressing potential public health crises. Based on survey data from China, we employed a Gradient Boosting Decision Tree (GBDT) model and conducted SHAP interpretability analysis. The results show that in the primary series of COVID−19 vaccines, the important factors include social norms, vaccine knowledge, anticipated regret, age, vaccine safety, social responsibility, education level, religious belief, vaccine effectiveness, and perceived severity. While for booster shots, the important variables include age, vaccination experience, vaccine knowledge, vaccine effectiveness, gender, perceived severity, concerns about the epidemic, social norms, anticipated regret, and sense of social responsibility. The differences in the composition and significance of these core predictive factors suggest that COVID-19 vaccine hesitancy is dynamically evolving. This pattern of evolution is manifested as a shift in the decision – making basis from social norms to subjective experiences, in the focus of vaccines from safety – first to effectiveness – priority, and in the decision – making mechanism from emotion – dominated to cognition – driven. The research findings inspire us that when formulating vaccination strategies, multiple factors need to be comprehensively considered. Moreover, strategies should be adjusted in a timely manner according to changes in the vaccination stages to align with the shift in public concerns and decision – making mechanisms.https://www.tandfonline.com/doi/10.1080/21645515.2025.2536898COVID-19 vaccinevaccine hesitancydynamic transformationmachine learning
spellingShingle Lei Li
Hui Jing
Yuqi Zhao
Shenghua Wu
Boyu Zhu
Influencing factors and dynamic changes of COVID-19 vaccine hesitancy in China: From the perspective of machine learning analysis
Human Vaccines & Immunotherapeutics
COVID-19 vaccine
vaccine hesitancy
dynamic transformation
machine learning
title Influencing factors and dynamic changes of COVID-19 vaccine hesitancy in China: From the perspective of machine learning analysis
title_full Influencing factors and dynamic changes of COVID-19 vaccine hesitancy in China: From the perspective of machine learning analysis
title_fullStr Influencing factors and dynamic changes of COVID-19 vaccine hesitancy in China: From the perspective of machine learning analysis
title_full_unstemmed Influencing factors and dynamic changes of COVID-19 vaccine hesitancy in China: From the perspective of machine learning analysis
title_short Influencing factors and dynamic changes of COVID-19 vaccine hesitancy in China: From the perspective of machine learning analysis
title_sort influencing factors and dynamic changes of covid 19 vaccine hesitancy in china from the perspective of machine learning analysis
topic COVID-19 vaccine
vaccine hesitancy
dynamic transformation
machine learning
url https://www.tandfonline.com/doi/10.1080/21645515.2025.2536898
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