Maternal B12 deficiency during pregnancy dysregulates fatty acid metabolism and induces inflammation in human adipose tissue

Maternal B12 deficiency during pregnancy dysregulates fatty acid metabolism and induces inflammation in human adipose tissue

Abstract Background Adipose tissue (AT) responds to excess calorie intake; however, the deficit in micronutrients accompanied by the modern lifestyle is often overlooked. Micronutrient deficiency in pregnancy, particularly vitamin B12 (B12), is commonly associated with higher adiposity, dyslipidemia...

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Bibliographic Details
Main Authors: Jinous Samavat, Joseph Boachie, Philip G. McTernan, Mark Christian, Ponnusamy Saravanan, Antonysunil Adaikalakoteswari
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Medicine
Subjects:
Vitamin B12
Adipose tissue
Low-grade inflammation
Lipid metabolism
Obesity
Pregnancy
Online Access:https://doi.org/10.1186/s12916-025-04056-4
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