Bee venom ameliorates gentamicin-induced kidney injury by restoring renal aquaporins and enhancing antioxidant and anti-inflammatory activities in rats

Bee venom ameliorates gentamicin-induced kidney injury by restoring renal aquaporins and enhancing antioxidant and anti-inflammatory activities in rats

Introduction:Gentamicin (GM) is a frequently used aminoglycoside for managing serious illnesses; nonetheless, renal complications limit its use. Bee venom (BV) is a biological toxin that exhibits anti-inflammatory and antioxidant activities. This study was designed to explore the mitigating effect o...

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Main Authors: Doaa Abdelrahaman, Obeid Shanab, Ahmed Abdeen, Afaf Abdelkader, Khalid M. Elazab, Hagar Kouriem, Zainab M. Maher, Amal S. Abu-Almakarem, Mohamed E. Mohamed, Yasser M. Elbastawisy, Mohamed G. Elsehrawy, Abdelnaser A. Badawy, Naglaa Mokhtar, Moaz A. Mojaddidi, Madaniah O. Zakari, Samah F. Ibrahim, Dania Abdelhady, Laila Mostafa
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
Subjects:
ethnopharmacology
aminoglycoside
bee venom
aquaporins
oxidative stress
renal pharmacology
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1525529/full
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