Spt5 orchestrates cryptic transcript suppression and transcriptional directionality
Abstract Spt5 is a well-conserved factor that manipulates multiple stages of transcription from promoter-proximal pausing (PPP) to termination. Recent studies have revealed an unexpected increase of antisense transcripts near promoters in cells expressing mutant Spt5. Here, we identify Spt5p-restric...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-10-01
|
| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-024-07014-7 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|